Glaucoma and Ocular Hypertension Clinical Trial
Official title:
To Check the Efficacy and Saftey of Combined Ex-PRESS Implantation Alone or With Phacoemulsification for Glaucoma Associated With Cataract
A prospective study reporting on Ex-PRESS shunt implantation alone or combined cataract and glaucoma surgery.
The occurrence of both glaucoma and clinically relevant cataract in the same individual is a
frequent condition, especially in the elderly population. Besides age, this might be related
to the possible role of antiglaucoma medications in the progression of lens opacity.When
both procedures are required, these can be performed separately or in combination.
Glaucoma filtering surgery is indicated when glaucomatous damage progresses despite the
lower level of intraocular pressure (IOP) obtained with pharmacological and/or laser
treatment.
The Ex-PRESS is a miniature stainless steel glaucoma device, developed as an alternative to
trabeculectomy and to the other types of glaucoma filtering surgery for patients with POAG.
This procedure would be theoretically more reproducible and simple to perform as well as
less traumatic to the ocular tissue than traditional filtering surgery. The implant is
inserted at the limbus under a conjunctival flap and diverts the aqueous humour from the
anterior chamber to the subconjunctival space, obtaining the formation of a conjunctival
filtration bleb, in a similar way to trabeculectomy. This procedure can be performed on its
own or in combination with phacoemulsification.
This study is aimed to test the efficacy and saftey of Ex-PRESS shunt implantation alone or
combined cataract and glaucoma surgery in patients with medically uncontrolled glaucoma and
cataract .
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