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Gingivitis clinical trials

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NCT ID: NCT01234948 Completed - Periodontitis Clinical Trials

Oral Malodour and Periodontal Disease-related Parameters

Start date: January 2008
Phase: N/A
Study type: Observational

The primary aim of the current study was to determine the association between halitosis detection (presence or absence) and periodontal status in non-smoking subjects, and also assess whether halitosis recordings were related to periodontal clinical parameters, tongue coating and quantities of two putative periodontal pathogens on the posterior region of the tongue determined by real-time PCR. Secondary, halitosis recordings were compared among subjects with chronic periodontitis, chronic generalized gingivitis and periodontal health.

NCT ID: NCT01224158 Completed - Clinical trials for Dental Devices, Home Care

Study of an Experimental Toothbrush for Treatment and Prevention of Gingivitis

Start date: September 13, 2010
Phase: N/A
Study type: Interventional

This study is 6 weeks long with 6 visits to a clinical site. People participating in this study will be asked to brush their teeth two times a day with a provided toothbrush. For one of those six weeks people will be asked to rinse with a mouthwash. During that time, people will use the mouthwash two times a day and will not be allowed to brush their teeth at all. The mouth, teeth, tongue and gums will be looked at by a dentist. At each visit, people will rinse with a pink liquid that will dye their mouths pink. The dye is temporary and will go away by the end of the day. They may also be asked to complete a short questionnaire about their experience.

NCT ID: NCT01197105 Unknown status - Gingivitis Clinical Trials

Evaluation Study of a Mouthwash Based on Schinus Terebinthifolius to Treat Gingivitis in Children

Start date: September 2010
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to evaluate the clinical efficacy of a mouthwash based on a natural product (Schinus terebinthifolius) used by children with gingivitis.

NCT ID: NCT01154257 Completed - Gingivitis Clinical Trials

Comparison of Swabs and Toothbrushes in Cleaning the Teeth of Mechanically Ventilated Patients

Start date: June 2010
Phase: N/A
Study type: Interventional

Cleaning the mouth is difficult in critically ill patients who require support from a breathing machine (ventilator). This is because the plastic (endotracheal) tube which is a necessary interface between patient and ventilator impedes cleaning. New evidence suggests that poor oral health may be linked to ventilator associated pneumonia. Throughout the world both toothbrushes and foam swabs are used to clean the teeth and remove dental plaque, however it is unknown if one method is more effective than the other. The purpose of this study is to establish which (if any) method is most effective at removing plaque in this population of patients.

NCT ID: NCT01142843 Completed - Gingivitis Clinical Trials

Preliminary Evidence of the Efficacy of a Mouthwash Containing 5% Propolis for the Control of Plaque and Gingivitis

MGP
Start date: August 2009
Phase: Phase 2
Study type: Interventional

Mouthwash based on medicinal plants and propolis can be easily found in the Brazilian market even if it has not been tested in reliable clinical trials on its efficacy or possible unpleasant side effects like the ones which alter the hard and soft oral tissues. The aim of this study was to obtain preliminary evidence of efficacy of an alcohol-free mouthwash containing 5% green propolis (MGP 5%) on the control of plaque and gingivitis. Were chosen twenty-five subjects that are UFMG employees and individuals who would begin treatment on an extension project called Supportive Periodontal Therapy at the Faculty of Dentistry of Federal University of Minas Gerais, Belo Horizonte, from August to December 2009. The subjects went through a dental prophylaxis before starting rinse. They were then instructed to rinse twice a day for a minute, immediately after brushing (morning and night), using the 10 ml of the MGP 5%. After 45 and 90 days using the product the individuals returned for a clinical evaluation which considered changes in the soft and hard oral tissues and involved collecting plaque and gingivitis indexes. On their last appointment the subjects answered a questionnaire about their level of appreciation and acceptability of the mouthwash. Compliance with the treatment was also evaluated through an attendance form. For the statistic analysis we used BioEstat 4.0 and Excel 2007.

NCT ID: NCT01103102 Completed - Gingivitis Clinical Trials

Dose-Response Study of Iocide Oral Rinse

Start date: April 2010
Phase: Phase 2
Study type: Interventional

The purpose of this study is to explore the dose-response relationship of Iocide oral rinse in a clinical trial of gingivitis. Approximately sixty (60) otherwise healthy subjects having gingivitis will be randomized into the 3-month study to provide 40 total evaluable subjects (10 per group). Each study participant will have four visits: a screening visit up to 21 days before the beginning of the trial, a baseline visit at day 1, and visits at weeks 8 and 12. The duration of the dose/range study will be three months to facilitate compliance and ensure timely completion of the Phase II study. Three dose/regimens will be evaluated against a placebo control oral rinse. Indices for gingivitis, plaque and bleeding will be scored and blood tests will be performed to determine the effect of the antimicrobial oral rinse on relative levels of biological markers of inflammation.

NCT ID: NCT01079910 Withdrawn - Gingivitis Clinical Trials

To Investigate the Clinical Efficacy of an Experimental Toothpaste

Start date: December 9, 2009
Phase: Phase 1
Study type: Interventional

The objective of this study is to evaluate the effect of an experimental toothpaste on maintaining gingival health over a 24 week period measured through modified gingival index, bleeding, plaque, and plaque bacteria. Prior to commencing study treatment, subjects will undergo a dental prophylaxis followed by a 2 week period of oral hygiene instruction and weekly professional tooth cleaning to bring the subjects to their optimum gingival health prior to commencing study treatment.

NCT ID: NCT00972803 Completed - Gingivitis Clinical Trials

The Effects of Pistacia Mutica on De Novo Dental Plaque Formation, Gingival Inflammation and Oral Microorganisms

Start date: May 2008
Phase: Phase 2
Study type: Interventional

Dental plaque is a well known etiologic factor for gingivitis. Recently, herbal extracts are a matter of scientific interest to inhibit plaque accumulation on teeth. The purpose of this study was to evaluate the effects of pistacia Mutica (PM) mouth wash on de novo dental plaque plaque formation, gingival inflammation indices and oral microorganisms.

NCT ID: NCT00964860 Completed - Gingivitis Clinical Trials

A Controlled Clinical Study to Determine the Gingivitis Benefit of Flossing

Start date: August 2009
Phase: Phase 3
Study type: Interventional

This is a randomized, controlled, examiner-blind, parallel group, four week clinical study comparing brushing plus flossing to brushing alone in 60 healthy adults with pre-existing gingivitis.

NCT ID: NCT00941668 Completed - Gingivitis Clinical Trials

Evaluate Inflammation Caused by Gingivitis in Adults

Start date: January 2007
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the anti-inflammatory efficacy of a dentifrice