Clinical Trials Logo
  1. Home
  2. Gestational Diabetes
  3. NCT05632055
  4. Details
NCT05632055 Clinical Trial

miRNA (microRNA) and FGF21 (Fibroblast Growth Factor-21) Profile in First Trimester and Gestational Diabetes Prediction

Gestational Diabetes Clinical Trial

Official title:
miRNA and FGF21 Profile in First Trimester and Efficacy of Gestational Diabetes Prediction and Pregnancy Outcomes

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT05632055
Other study ID # OBG-2563-07494
Secondary ID
Status Active, not recruiting
Phase
First received
Last updated
Start date August 26, 2000
Est. completion date August 31, 2023

Study information
Verified date December 2022
Source ChaingMai University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational [Patient Registry]

Clinical Trial Summary

The goal of this observational study is to compare miRNA and FGF21 in pregnancy with and without GDM (Gestational Diabetes) The main question it aims to answer that miRNA and FGF21 are different between two groups. Participants will be retrieved blood sample during first trimester and undergone 100 gm OGTT (oral glucose challenge test) during 24-28 weeks of gestation.

Description:

Pregnant women who attended antenatal care at Maharaj Nakorn Chiang Mai hospital during first trimester were recruited. Participants received routine standard prenatal care except, 1. additional blood test during 11-13 week 6 days (Blood was collected for further analysis) 2. performed 75gm OGTT during 24-28 week Baseline data and pregnancy outcome were reviewed.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 160
Est. completion date August 31, 2023
Est. primary completion date November 21, 2022
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Female
Age group N/A and older
Eligibility Inclusion Criteria: - singleton pregnant women who attend at our clinic in first trimester Exclusion Criteria: - known underlying disease such as chronic hypertension, pregestational diabetes, SLE - normal structural fetal anatomical screening - incomplete obstetric data

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• blood draw
Blood test for miRNA and FGF21. However, the laboratory result is not reported and not involved in management

Locations
Country Name City State
Thailand Maharaj Nakorn ChiangMai Hospital ChiangMai

Sponsors (1)
Lead Sponsor Collaborator
ChaingMai University

Country where clinical trial is conducted

Thailand, 

Outcome
Type Measure Description Time frame Safety issue
Primary miRNA profile miRNA profile in first trimester of pregnancy and efficacy for GDM prediction within 1 month after blood drawn
Secondary FGF21 profile FGF21 profile in first trimester of pregnancy and efficacy for GDM prediction 6 months after blood drawn
See also
  Status Clinical Trial Phase
Recruiting NCT05081037 - Integrated Hyperglycaemia Incentivised Postnatal Surveillance Study (I-HIPS) N/A
Active, not recruiting NCT03249896 - Web/Smartphone-based Lifestyle Coaching Program in Pregnant Women With Gestational Diabetes N/A
Terminated NCT03749889 - Low Carb vs Normal Carb in Pregnancy N/A
Completed NCT03859193 - Education Nutritional Video for Gestational Diabetics N/A
Recruiting NCT05037526 - Utility of Real Time Continuous Glucose Monitoring in the Care of Gestational Diabetes Versus Standard Care in Pregnancy Outcomes N/A
Completed NCT06178250 - Placenta, Fetal Liver, Sectional Ductus Venosus Volumes Examined by Three-dimensional Ultrasound in the Second Trimester N/A
Not yet recruiting NCT06310356 - Continuous Glucose Monitoring for Women With Gestational Diabetes N/A
Not yet recruiting NCT06445530 - Nutrition Optimization and Community Upliftment for Postpartum Recovery N/A
Recruiting NCT02590016 - Glucose Control During Labour in Gestational Diabetes Mellitus With Insulin Treatment: A Randomized Controlled Trial Phase 4
Not yet recruiting NCT00883259 - Metformin and Gestational Diabetes in High-risk Patients: a RCTs Phase 4
Withdrawn NCT01947699 - Glycemic Profile in Women With Gestational Diabetes Treated With Glyburide Phase 4
Recruiting NCT03008824 - Micronutrients in Pregnancy as a Risk Factor for Diabetes and Effects on Mother and Baby N/A
Active, not recruiting NCT01340924 - Relationship Between Gestational Diabetes and Type 2 Diabetes
Completed NCT00534105 - Lipid Metabolism in Gestational Diabetes N/A
Recruiting NCT00371306 - Comparison of Glucovance to Insulin for Diabetes During Pregnancy N/A
Completed NCT03388723 - Intergenerational Programming of Diabesity in Offspring of Women With Gestational Diabetes Mellitus
Recruiting NCT04521712 - Postpartum Glycemia in Women at Risk For Persistent Hyperglycemia N/A
Enrolling by invitation NCT03307486 - Gestational Diabetes: a Cohort Study N/A
Active, not recruiting NCT03301792 - Group Versus Traditional Prenatal Care for Diabetes N/A
Enrolling by invitation NCT05603793 - YoUng Adolescents' behaViour, musculoskeletAl heAlth, Growth & Nutrition