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Genital Diseases, Male clinical trials

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NCT ID: NCT03677336 Completed - Infertility Clinical Trials

Oral Dydrogesterone (OD) Versus Micronized Vaginal Progesterone (MVP) for Luteal Phase Support (LPS) in IVF/ICSI

Start date: May 1, 2019
Phase: Phase 4
Study type: Interventional

Female inability to conceive a child. The purpose of this prospective randomized, double-blinded, double dummy, two-arm cross-over study is to investigate the difference on histological, transcriptional and immunological level in endometrium between 3x10mg Dydrogesterone oral tablets and 3x200 mg Micronized progesterone intravaginal capsules for the luteal support in egg cell donors. Beside that, the pharmacokinetics, the impact on the peripheral immunology (by blood sampling) and the microbiota (by genital swabs) will be investigated.

NCT ID: NCT02074644 Completed - Clinical trials for Lower Urinary Tract Symptoms

Clinical Trial of Prostatic Arterial Embolization Versus a Sham Procedure to Treat Benign Prostatic Hyperplasia

Start date: September 2, 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether prostatic arterial embolization (PAE) compared is an effective and safe treatment for benign prostatic hyperplasia in patients with severe lower urinary tract symptoms not adequately controlled by medical therapy with alpha-blockers, as assessed by the the International Prostate Symptom Score (IPSS) after 6 months. Patients will be randomized on a 1:1 ratio to PAE or to a sham procedure and evaluated at 1, 3 and 6 months. Patients randomized to the sham procedure will be offered the possibility of performing PAE after 6 months. All patients may participate on an optional 6-months extension study.

NCT ID: NCT01316458 Completed - Prostatic Neoplasm Clinical Trials

Glivec in Prostate Cancer Patients With Rising PSA Following Radical Prostectomy

Start date: June 2003
Phase: Phase 2
Study type: Interventional

To investigate the ability of 600 mg of Glivec®, given once daily by mouth to patients with rising PSA following radical prostatectomy, to produce a sustained biochemical response during the first 6 months of treatment.

NCT ID: NCT00425984 Completed - HIV Infections Clinical Trials

Male Circumcision for HIV Prevention in Rakai, Uganda

Start date: August 2002
Phase: Phase 3
Study type: Interventional

Circumcision in HIV unifected men may reduce the likelihood of becoming infected with HIV, reduce sexually transmitted infections (STIs) in men, not engender increases in sexual risk behaviors, and be acceptable to men as a procedure for preventing HIV. The purpose of this study is to evaluate circumcision in HIV uninfected men in terms of safety and ability to prevent HIV infection.

NCT ID: NCT00012480 Completed - Male Infertility Clinical Trials

Effect of Environmental Exposures on the Egg Fertilizing Ability of Human Sperm

Start date: August 2002
Phase: N/A
Study type: Observational

Our data indicate that environmental exposure to the heavy metal lead are more widespread than currently appreciated and that such exposures are associated with the production of human male subfertility. Lead's effects are observed in male partners of infertile couples attending an IVF clinical, in men acting as semen donors in an artificial insemination program and in men representative of the general public. Our goal is to identify the mechanism(s) underlying lead's anti-fertility action.