Clinical Trials Logo
  1. Home
  2. Gastric Intestinal Metaplasia
  3. NCT05345314
  4. Details
NCT05345314 Clinical Trial

Endoscopic Grading of Intestinal Metaplasia

Gastric Intestinal Metaplasia Clinical Trial

Official title:
Endoscopic Grading of Gastric Intestinal Metaplasia: a Validation Study in Korea

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05345314
Other study ID # SCH-EGD-2022
Secondary ID
Status Completed
Phase
First received
Last updated
Start date March 1, 2022
Est. completion date April 24, 2023

Study information
Verified date April 2023
Source Soonchunhyang University Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Long-term Helicobacter pylori infection causes premalignant gastric conditions, such as atrophic gastritis and intestinal metaplasia. Image-enhanced endoscopy techniques such as narrow-band imaging (NBI) and magnifying endoscopy improve the diagnosis of gastric intestinal metaplasia (GIM). However, there are no comparative data on the utility of NBI and magnifying endoscopy for diagnosing GIM.

Description:

This study aims to evaluate the diagnostic performance of NBI and magnifying endoscopy for GIM in a country with high risk of gastric premalignant lesions.

Recruitment information / eligibility
Status Completed
Enrollment 242
Est. completion date April 24, 2023
Est. primary completion date February 28, 2023
Accepts healthy volunteers
Gender All
Age group 20 Years to 80 Years
Eligibility Inclusion Criteria: - Gastroscopy can be performed - Pathological analysis can be performed for analysis of gastric atrophy and intestinal metaplasia Exclusion Criteria: - Age < 20 or > 80 years - Anemia (serum hemoglobin level < 10 g/dL) - Severe systemic disease - Advanced chronic liver disease - Use of certain medications, including proton pump inhibitors, H2-receptor antagonists, or antibiotics - History of H. pylori eradication - History of gastric surgery - Recent history of upper gastrointestinal bleeding

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• Narrow-band imaging endoscopy
During endoscopy, gastric mucosal patterns would be examined by magnifying narrow-band imaging.

Locations
Country Name City State
Korea, Republic of Digestive Disease Center, Soonchunhyang University Hospital Seoul

Sponsors (1)
Lead Sponsor Collaborator
Soonchunhyang University Hospital

Country where clinical trial is conducted

Korea, Republic of, 

Outcome
Type Measure Description Time frame Safety issue
Primary Gastric intestinal metaplasia Gastric intestinal metaplasia would be assessed using pathological examination. 4 weeks
Secondary Degree of chronic gastritis Gastric atrophy would be evaluated on the basis of histopathological examination (updated Sydney system). 4 weeks
See also
  Status Clinical Trial Phase
Recruiting NCT02428426 - Mucosal Microbiome in Human Gastric Intestinal Metaplasia and Duodenal Tissue. N/A
Completed NCT02846688 - Gene Expression Profiling in Human Gastric Intestinal Metaplasia Mucosa and Duodenal Mucosa N/A
Unknown status NCT01491724 - The Learning Curve of Probe-based Confocal Laser Endomicroscopy (pCLE) Images Interpretation in Gastric Intestinal Metaplasia (GIM) N/A
Active, not recruiting NCT02794428 - Chemoprevention of Gastric Carcinogenesis Phase 2
Completed NCT03672708 - Confocal Laser Endomicroscopy With Cresyl Violet for in Vivo Diagnosis of Gastric Intestinal Metaplasia N/A
Not yet recruiting NCT02930616 - A Comparison of pCLE Based Targeted Biopsy and WLE Based Standard Biopsy in Staging the Operative Link on Gastric Intestinal Metaplasia (OLGIM): A Randomized，Cross-over Study Phase 4
Recruiting NCT01490541 - The Predictive Scores for Gastric Cancer in Gastric Intestinal Metaplasia (GIM) Patient: a Recommendation for Thai Population N/A
Recruiting NCT05657080 - Cytosponge for Gastric Intestinal Metaplasia
Recruiting NCT04869618 - Validation of an Artificial Intelligence System Based on Raman Spectroscopy for Diagnosis of Gastric Premalignant Lesions and Early Gastric Cancer N/A
Recruiting NCT02516735 - I-scan With Magnification for the Detection of Gastric Intestinal Metaplasia N/A
Recruiting NCT02534818 - Different Fluorescein Sodium Dosage for the Detection of Gastric Intestinal Metaplasia Phase 4
Recruiting NCT01646528 - The Value of Black Spots in Diagnosing Gastric Intestinal Metaplasia by Confocal Laser Endomicroscopy N/A
Recruiting NCT03250091 - Surveillance of Patients With Precancerous Lesions of the Stomach
Not yet recruiting NCT04843397 - Diagnostic Performance Indicators in Upper GI Endoscopy:PROSPERO Study
Completed NCT04348266 - RFA for GIM Treatment N/A
Recruiting NCT02725034 - Diagnosis of Gastric Intestinal Metaplasia With High Definition Endoscopy and Optic Enhancement N/A
Completed NCT01945177 - RCT: WLE vs. NBI in Upper Gastrointestinal Endoscopy N/A
Not yet recruiting NCT01642797 - Confocal Laser Endomicroscopy for the Diagnosis of Gastric Intestinal Metaplasia, Intraepithelial Neoplasia, and Carcinoma N/A
Completed NCT01384201 - Confocal Endomicroscopy Detection of Gastric Preneoplasia and Neoplasia N/A
Recruiting NCT05447221 - Automatic Evaluation of the Severity of Gastric Intestinal Metaplasia With Pathology Artificial Intelligence Diagnosis System