Gastric Cancer Clinical Trial
Official title:
Surveillance Strategies of Patients With Precancerous Conditions and Lesions in the Stomach
The project will aim to identify and determine subgroups of patients with different risks of progression to gastric cancer and to assess appropriate follow-up intervals. Implementing risk stratification only high risk individuals will be offered and performed endoscopic surveillance.
Gastric cancer is still an important healthcare problem with significant mortality rates.
Latvia is a high incidence country of gastric cancer. Unfortunately most of the gastric
cancer cases in Latvia are diagnosed at late stages when the treatment is substantially less
effective.
Ideally, gastric cancer could be prevented by detecting gastric precancerous
conditions/lesions and identifying those individuals at high-risk of progressing to cancer to
the follow-up.
Population based endoscopic screening for gastric cancer is not recommended for the early
detection of gastric cancer generally deemed not to be cost-effective.
However, in the absence of screening, patients present with advanced disease, and prognosis
is poor.
Targeted endoscopic surveillance strategies for gastric cancer should be introduced following
the principles of the recent European guidelines: Management of precancerous conditions and
lesions in the stomach (MAPS) (Dinis-Ribeiro, Areia et al. 2012).
The project will aim to identify and determine subgroups of patients with different risks of
progression to gastric cancer and to assess appropriate follow-up intervals. Implementing
risk stratification only high risk individuals will be offered endoscopic surveillance.
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