Clinical Trials Logo
  1. Home
  2. Gastric Intestinal Metaplasia
  3. NCT05288153

Metformin Efficacy and Safety for Gastric Intestinal Metaplasia

Gastric Intestinal Metaplasia Clinical Trial

Official title:
Metformin Efficacy and Safety for Gastric Intestinal Metaplasia: a Randomized Controlled Trial

Clinical Trial Summary

Gastric intestinal metaplasia significantly increases the risk of gastric cancer. Metformin, a biguanide, which is widely used for treating diabetes mellitus, has recently been suggested to have a suppressive effect on tumorigenesis and cancer cell growth. The investigators devised a prospective randomized controlled trial to evaluate the chemopreventive effect of metformin against gastric intestinal metaplasia and the safety of this drug in non-diabetic gastric intestinal metaplasia patients.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05288153
Study type Interventional
Source Xijing Hospital of Digestive Diseases
Contact
Status Completed
Phase Phase 4
Start date April 1, 2022
Completion date October 31, 2023
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT02428426 - Mucosal Microbiome in Human Gastric Intestinal Metaplasia and Duodenal Tissue. N/A
Completed NCT02846688 - Gene Expression Profiling in Human Gastric Intestinal Metaplasia Mucosa and Duodenal Mucosa N/A
Unknown status NCT01491724 - The Learning Curve of Probe-based Confocal Laser Endomicroscopy (pCLE) Images Interpretation in Gastric Intestinal Metaplasia (GIM) N/A
Active, not recruiting NCT02794428 - Chemoprevention of Gastric Carcinogenesis Phase 2
Completed NCT03672708 - Confocal Laser Endomicroscopy With Cresyl Violet for in Vivo Diagnosis of Gastric Intestinal Metaplasia N/A
Not yet recruiting NCT02930616 - A Comparison of pCLE Based Targeted Biopsy and WLE Based Standard Biopsy in Staging the Operative Link on Gastric Intestinal Metaplasia (OLGIM): A Randomized，Cross-over Study Phase 4
Recruiting NCT01490541 - The Predictive Scores for Gastric Cancer in Gastric Intestinal Metaplasia (GIM) Patient: a Recommendation for Thai Population N/A
Recruiting NCT04869618 - Validation of an Artificial Intelligence System Based on Raman Spectroscopy for Diagnosis of Gastric Premalignant Lesions and Early Gastric Cancer N/A
Recruiting NCT02516735 - I-scan With Magnification for the Detection of Gastric Intestinal Metaplasia N/A
Completed NCT05345314 - Endoscopic Grading of Intestinal Metaplasia
Recruiting NCT02534818 - Different Fluorescein Sodium Dosage for the Detection of Gastric Intestinal Metaplasia Phase 4
Recruiting NCT01646528 - The Value of Black Spots in Diagnosing Gastric Intestinal Metaplasia by Confocal Laser Endomicroscopy N/A
Recruiting NCT03250091 - Surveillance of Patients With Precancerous Lesions of the Stomach
Not yet recruiting NCT04843397 - Diagnostic Performance Indicators in Upper GI Endoscopy:PROSPERO Study
Completed NCT04348266 - RFA for GIM Treatment N/A
Recruiting NCT02725034 - Diagnosis of Gastric Intestinal Metaplasia With High Definition Endoscopy and Optic Enhancement N/A
Completed NCT01945177 - RCT: WLE vs. NBI in Upper Gastrointestinal Endoscopy N/A
Not yet recruiting NCT05657080 - Cytosponge for Gastric Intestinal Metaplasia
Not yet recruiting NCT01642797 - Confocal Laser Endomicroscopy for the Diagnosis of Gastric Intestinal Metaplasia, Intraepithelial Neoplasia, and Carcinoma N/A
Completed NCT01384201 - Confocal Endomicroscopy Detection of Gastric Preneoplasia and Neoplasia N/A