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Gastric Cancer clinical trials

View clinical trials related to Gastric Cancer.

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NCT ID: NCT03342417 Terminated - Ovarian Cancer Clinical Trials

Combination of Nivolumab and Ipilimumab in Breast, Ovarian and Gastric Cancer Patients

Start date: February 14, 2018
Phase: Phase 2
Study type: Interventional

Safety and tolerability of combination of Nivolumab and Ipilimumab will be studied in patients with 3 different types of cancers in 3 parts of the study, as shown below: Part 1 - Neoadjuvant Therapy of Breast Cancer; Part 2 - Therapy of Ovarian Cancer; and Part 3 - Therapy of Gastric Cancer.

NCT ID: NCT03333967 Recruiting - Gastric Cancer Clinical Trials

The Real World Study of Apatinib for Gastric Cancer Treatment in Anhui Province

Start date: September 1, 2017
Phase: N/A
Study type: Observational

The investigators conduct the real world study to explore the efficacy and safety of Apatinib in gastric cancer .

NCT ID: NCT03332433 Completed - Gastric Cancer Clinical Trials

High-flow Nasal Cannula Oxygenation Decrease Hypoxia in Gastroscopy Sedated by Propofol

HONCHO
Start date: November 10, 2017
Phase: N/A
Study type: Interventional

Hypoxia is the most common adverse events during sedated gastroscopy. In present study, high-flow nasal cannula oxygenation will be utilized in order to reduce the hypoxia. At the same time the feasibility and safety will be evaluated.

NCT ID: NCT03329950 Completed - Breast Cancer Clinical Trials

A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignancies

Start date: December 1, 2017
Phase: Phase 1
Study type: Interventional

This is a study to determine the maximum tolerated dose (MTD) for CDX-1140 (CD40 antibody), either alone or in combination with CDX-301 (FLT3L), pembrolizumab, or chemotherapy and to further evaluate its tolerability and efficacy in expansion cohorts once the MTD is determined.

NCT ID: NCT03321630 Completed - Gastric Cancer Clinical Trials

A Phase II a Study of Lenvatinib, a Multi-targeted Tyrosine Kinase Inhibitor, Combined With Pembrolizumab (PD-1 Inhibitor) for the Treatment of Metastatic Gastroesophageal Cancer Patients Who Have Progressed on First or Subsequent Line Therapies

Start date: October 24, 2017
Phase: Phase 2
Study type: Interventional

This is an open label, single arm phase II study, to determine the overall response rate for the combination of lenvatinib and pemrolizumab in patients with metastatic gastroesophageal cancer who have progressed on first or subsequent line therapies. Given the significant cross talk between angiogenesis and the immune response, combined therapy with lenvatinib and pemrolizumab in advanced gastroesophageal cancer patient will provide improved outcomes compared to standard treatment with currently approved agents.

NCT ID: NCT03314649 Completed - Gastric Cancer Clinical Trials

Peritoneal Lavage for Early Detecting Gene Mutation of Peritoneal Metastasis of Gastric Cancer

Start date: December 21, 2017
Phase:
Study type: Observational

Our study aims to improve sensitivity and accuracy of detecting abdominal free cancer cells in patients with gastric cancer.

NCT ID: NCT03283761 Completed - Gastric Cancer Clinical Trials

FOLFOX-A in the Treatment of Metastatic or Advanced Unresectable Gastric, Gastro-Esophageal Junction Adenocarcinoma

Start date: September 21, 2017
Phase: Phase 2
Study type: Interventional

This is an open label, single-arm phase II, multi-institutional trial to evaluate the efficacy and safety of the combination of nab-paclitaxel and FOLFOX (FOLFOX-A) as first line therapy for patients diagnosed with histologically-confirmed advanced gastric/GEJ adenocarcinoma.

NCT ID: NCT03277144 Recruiting - Gastric Cancer Clinical Trials

Incidence of Duodenal Stump Fistula After Gastrectomy for Gastric Cancer. A Randomized Controlled Trial

DRTST
Start date: September 11, 2017
Phase: N/A
Study type: Interventional

The goal of this trial is to demonstrate that the use of Tri-Staple Technology for duodenal resection during open gastrectomy for cancer is safer than the use of other conventional methods of resection/closure of the duodenum and that the incidence of duodenal fistula can be decreased to that observed after the use of this technology in Laparoscopic and robotic gastrectomy, therefore almost three times lower than that currently reported in literature. Participating centres must have an annual volume of at least 20 gastrectomies per year.

NCT ID: NCT03276156 Recruiting - Gastric Cancer Clinical Trials

Apatinib in Combination With S-1 as Second-Line Treatment in Patients With Advanced Gastric Cancer

Start date: February 23, 2016
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the maximum tolerated dose (MTD)and safety of Apatinib combined with S-1 as Second-line therapy for patients with advanced gastric or gastroesophageal junction adenocarcinoma.

NCT ID: NCT03273920 Not yet recruiting - Gastric Cancer Clinical Trials

Robotic Versus Laparoscopic Distal Gastrectomy With D2 Lymphadenectomy for Locally Advanced Gastric Cancer

Start date: September 25, 2017
Phase: N/A
Study type: Interventional

This study is an investigator-initiated, randomized, controlled, parallel group, and non-inferiority trial comparing robot-assisted gastrectomy with D2 nodal dissection for locally advanced gastric cancer patients with laparoscopic procedure.