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Gallbladder Diseases clinical trials

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NCT ID: NCT06364865 Not yet recruiting - Acute Cholecystitis Clinical Trials

AE05ML Device for ML Hem-o-lok Polymer Clip Delivery in Laparoscopic Surgical Procedures Observational Registery Study

AE05ML
Start date: April 22, 2024
Phase:
Study type: Observational [Patient Registry]

This clinical registry study aims to evaluate the safety and effectiveness of the AE05ML device for ligating vessels and tissue structures during laparoscopic surgery using Hem-o-lok® Medium Large (ML) polymer clips. The primary objective is to assess the device's safety and performance, with secondary objectives focusing on device performance characteristics and operator feedback.

NCT ID: NCT06315179 Not yet recruiting - Ulcerative Colitis Clinical Trials

Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE)

STRIDE
Start date: April 2024
Phase:
Study type: Observational [Patient Registry]

This is a prospective observational study collecting long-term clinical data and samples for research in pediatric inflammatory bowel disease (IBD) patients with gut inflammation and a control cohort of pediatric patients with disorders of the brain-gut interactions (DBGI) with no detectable gut inflammation.

NCT ID: NCT05927870 Not yet recruiting - Clinical trials for Gall Bladder Disease

Ultrasound Guided Percutaneous Cholecystostomy.

Start date: August 1, 2023
Phase: N/A
Study type: Interventional

Surgical cholecystostomy has proven value in the management of both inflammatory and obstructive biliary tract disease

NCT ID: NCT05724277 Not yet recruiting - Clinical trials for Laparoscopic Cholecystectomy

The Effect of Mindfulness Meditation and Virtual Reality on Laparoscopic Cholecystectomy Patients

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

In this study, it is aimed to compare the effects of short-term mindfulness meditation based on Human Caring Theory and virtual reality on patients scheduled for laparoscopic cholecystectomy.

NCT ID: NCT05339282 Not yet recruiting - Clinical trials for Cholecystitis, Acute

Effectiveness of Empirical Antibiotic Use in Mild to Moderate Acute Inflammatory Gallbladder Disease

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

This clinical trial is an exploratory clinical trial that evaluates the necessity and effectiveness of empirical antibiotic use in mild and moderate acute inflammatory gallbladder diseases that require surgery, and the incidence of postoperative infection-related complications is compared.

NCT ID: NCT04922528 Not yet recruiting - Choledocholithiasis Clinical Trials

Visualization of the Extrahepatic biliaRy Tree Trial

VERT
Start date: August 2021
Phase: N/A
Study type: Interventional

This study is a prospective randomized controlled trial evaluating the use of a fluorescent dye, indocyanine green (ICG), in the identification of important bile duct anatomy during emergent same-admission cholecystectomy. Participants will be randomized into either the control arm, which uses the standard of care white light during laparoscopy or the intervention arm, which will use ICG fluorescent cholangiography as an adjunct to white light to visualize the biliary anatomy. The investigators hypothesize that the use of fluorescent cholangiography will increase the rates of identification of important biliary anatomy during laparoscopic cholecystectomy. The effectiveness, feasibility, and safety will be compared between the two groups using a post-operative survey form the surgeons will complete prior to exiting the operating room.

NCT ID: NCT04321902 Not yet recruiting - Clinical trials for Cholecystitis, Acute

Empirical Antibiotics in Acute Inflammatory Gallbladder Disease

Start date: April 2, 2020
Phase: N/A
Study type: Interventional

In this study, the investigators compared the surgical outcomes according to the type of antibiotics before surgery in patients who did not have evidence of systemic infection during acute cholecystitis. The primary purpose of the study was to determine the type of preoperative antibiotics in patients who were scheduled for cholecystectomy, because of the mild (grade I) or moderate (grade 2) acute inflammatory gallbladder disease without gallbladder perforation. The investigators compared the incidence of postoperative complications according to the types of preoperative antibiotics(the first-generation vs second-generation cephalosporin). The secondary purpose of the study was to confirm the clinical efficacy of first-generation cephalosporins following the use of empirical antibiotics. And the investigators compare with postoperative pain, postoperative hospital stay, re-hospitalization, and need for additional treatment. In addition, the investigators compare the postoperative complications, such as atelectasis and postoperative ileus.

NCT ID: NCT03981315 Not yet recruiting - Cholelithiasis Clinical Trials

Bile Composition in Healthy and Gallstones Patients

Start date: October 2019
Phase:
Study type: Observational [Patient Registry]

Determine differences between lithogenic and non-lithogenic bile composition.

NCT ID: NCT03762837 Not yet recruiting - Healthy Clinical Trials

Multicenter Prospective Cohort Study of Risk Factors for Gallbladder Cancer

Start date: April 1, 2019
Phase:
Study type: Observational [Patient Registry]

This trial is a prospective study, the main purpose of the study is to investigate the association between benign gallbladder disease and gallbladder carcinoma; to explain the timing of intervention, intervention and early prevention of benign gallbladder disease; according to the national epidemiology of gallbladder cancer Center Clinical Research (unpublished), 2000 National Cholecystoma Clinical Epidemiology Report, and 2005 Clinical Analysis of 2379 Cases of Gallbladder Carcinoma in 17 Hospitals in Five Northwest Provinces, Pre-experimental data, using samples The volume estimation formula, α = 0.05, β = 0.1, plans to enroll 100,000 people.Half of participants is someone with Biliary benign disease,while the other half is healthy.

NCT ID: NCT03533322 Not yet recruiting - Clinical trials for Gall Bladder Disease

Gall Bladder Status Among Children With Chronic Haemolytic Anemia

GBSACWCHA
Start date: October 1, 2018
Phase:
Study type: Observational

Gall bladder status among children with chronic haemolytic anemia attending to Assuit University Children Hospital. Hemolysis is defined as the premature destruction of red blood cells (RBCs) (a shortened RBC life span). Anemia results when the rate of destruction exceeds the capacity of the marrow to produce RBCs. Normal RBC survival time is 110-120 days (half-life: 55-60 days), and thus, approximately 0.85% of the most senescent RBCs are removed and replaced each day. Patients with chronic haemolytic anemia are subjected to many complications of chronic haemolytic anemia e.g anemic heart failure, complications of blood transfusion as hepatitis and AIDS, hypersplenism, haemosiderosis ,among them there is incidence of gallbladder stone formation. This work aims to a) to determine the prevalence of gall bladder diseases among patient with chronic haemolytic anemia. b) to determine the risk factors of gall bladder diseases among patients with chronic haemolytic anemia.