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Furcation Defects clinical trials

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NCT ID: NCT06270303 Not yet recruiting - Periodontitis Clinical Trials

Use of a Bone Substitute Material in the Surgical Therapy of Furcation Defects

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

The aim of this randomized clinical trial is to evaluate the potential benefit of the use of a bone substitute material in the treatment of furcation degree II-involved molars. The main question it aims to answer is: What is the benefit of the adjunctive use of a bone substitute material in the surgical treatment of furcation degree II-involved molars when compared to open-flap debridement alone? 200 patients with ≥1 molar presenting with a furcation defect degree II will be included and randomized to either control (open-flap debridement) or test treatment (open-flap debridement + bone substitute material). The primary outcome of the study is furcation closure defined as absence of clinically detectable furcation involvement degree >I. Secondary outcomes include changes in bleeding on probing, probing depth, vertical and horizontal attachment levels, soft tissue level, marginal bone level, need for surgical retreatment, tooth loss, patient-reported outcomes and adverse events. A composite outcome based on furcation closure (degree ≤I) in combination with shallow probing depth (≤5 mm) and absence of bleeding on probing will also be evaluated.

NCT ID: NCT06116487 Not yet recruiting - Periodontitis Clinical Trials

MRI as Alternative to CBCT for the Assessment of Furcation Involvement in Molars

Start date: November 20, 2023
Phase:
Study type: Observational

Aim of this prospective study is to compare magnetic resonance imaging (MRI) and cone beam computed tomography (CBCT) to diagnose furcation involvement (FI) in molars in patients with periodontitis. The focus is on the differentiation of grad II and III according to Hamp et al. 1975. 140 molars (70 upper and 70 lower) will be investigated with CBCT and MRI. Due to the absence of ionic radiation MRI might be a radiation free diagnostic tool to assess FI in the future without harmful radiation for the patient. Patients of the Dental Clinic, Medical University of Vienna, who need a CBCT and have a clinically diagnosed FI can be a participant of this clinical trial and do in addition to their CBCT a MRI. The accuracy of MRI will be compared to the diagnostic gold standard CBCT. If patients need additional periodontal treatment, e.g., periodontal surgery, a subgroup will also be analysed with intraoperative measurements.

NCT ID: NCT05721313 Not yet recruiting - Clinical trials for Periodontal Diseases

Vital Root Amputation in Molars With Advanced Periodontal Furcation Involvement: a Preliminary Study

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test in 10 patients with advanced furcation involvement on molars. The main question[s] it aims to answer are: • Is it possible to carry out root resection without endodontic treatment on molars? Tooth vitality will be checked (positive response to cold test). Root resection will be carried out under local anestesia. Following visits will be carried out for re-evaluation/maintenance according to clinical care every 3 mounths until 3 years follow-up.

NCT ID: NCT05481580 Not yet recruiting - Furcation Defects Clinical Trials

Restorations and Furcation Involvement on Molars

Start date: September 1, 2022
Phase:
Study type: Observational

The aim of this study will be to analyze the relationship between the presence of second class restorations (interproximal fillings) or prostheses (crowns, bridges) on molar teeth and the presence of bone resorption between the roots of the latter. Patients with this type of restorations will be identified and a non-interventional clinical and radiographic analysis will be conducted.

NCT ID: NCT04851548 Not yet recruiting - Furcation Defects Clinical Trials

Evaluate the Effect of Hyaluronic Acid in the Treatment of Furcation Involvement

Start date: September 23, 2021
Phase: N/A
Study type: Interventional

the effect Hyaluronic Acid in the Treatment of Furcation Involvement

NCT ID: NCT03804086 Not yet recruiting - Periodontitis Clinical Trials

Evaluation of Advanced PRF Combined With Nano-crystalline Hydroxyapatite for Management of Grade II Furcation Defects

Start date: February 2019
Phase: N/A
Study type: Interventional

this study is to evaluate the use of advanced platelet rich fibrin (A-PRF) + nano-crystalline hydroxyapatite bone substitute combined with open flap debridement (OPD) versus open flap debridement alone in the management of mandibular molar grade II defects. In the management of mandibular molar grade II furcation defects, no difference exists in gain of horizontal clinical attachment level between the use of advanced platelet rich fibrin (A-PRF) + with nano-crystalline hydroxyapatite bone substitute combined with open flap debridement (OPD) and open flap debridement (OPD) alone .