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Fractures, Bone clinical trials

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NCT ID: NCT01435070 Recruiting - Clinical trials for Distal Radius Fractures

Functional Outcome Following Fracture of the Distal Radius

Start date: January 2011
Phase: N/A
Study type: Observational

Patients attending the University Hospital Coventry UK with a broken wrist requiring an operation, will be invited to enter the study. At the first visit, they will have an xray of the wrist and will be asked to complete a number of questionnaires. The questions are to determine if they normally have pain in the wrist and how well they can perform their daily activities. The patient will then have an operation, and the fracture in the wrist will be held in the correct position with either a metal plate and screws or wires. At 6 weeks following the operation the patient will be reassessed and an xray will be taken. At 3 months, 6 months and 12 months after the operation patients will perform tests to assess the strength of their grip, pinch and movement of their wrist. In addition they will complete the the same questionnaires from their first visit. At the 12 month visit patients will have another xray.

NCT ID: NCT01401712 Recruiting - Clinical trials for 3 or More Rib Fractures

Optimal Method of Pain Management in Patients With Multiple Rib Fractures

Start date: October 2012
Phase: N/A
Study type: Interventional

Rib fractures are a common injury of trauma patients and can cause significant pain which, if inadequately treated, can lead to impaired breathing, lung collapse, and respiratory failure. Hence, it is crucial to manage pain associated with rib fractures. Currently, epidurals are used to treat the pain, but placement can be risky as rib fractures are often associated with other injuries and complications. An alternative pain management option is the ON-Q® Pain Relief System. It is an FDA-approved device that automatically and continuously delivers medication to the region of the thoracic intercostal nerves. One study by Truitt et al (2010)demonstrated that the ON-Q® system effectively reduced pain and increased lung volumes after one hour, in patients with three or more rib fractures. However, that study sample was small and did not have a comparison group. In this study, we will compare two groups: 1) ON-Q system and 2) epidural analgesia. We hypothesize that trauma patients with three or more rib fractures, who receive pain management through the ON-Q® Pain Relief System achieve discharge criteria earlier and thus have a shorter hospital length of stay (LOS) when compared with epidural analgesia.

NCT ID: NCT01354535 Recruiting - Femur Fractures Clinical Trials

Types of Fixation of Vancouver B1 Periprosthetic Fractures

Start date: February 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to compare two different but standard treatments for the fixation of Vancouver B1 periprosthetic. The investigators aim to compare open reduction internal fixation using a locked plating system versus plating and strut allograft with cerclage wiring to determine which treatment results in a faster return to function as measured by the TUG test at 6 weeks post-op.

NCT ID: NCT01281826 Recruiting - Clinical trials for Spinal Compression Fracture

Dual-energy CT in Detecting Bone Marrow Edema of Vertebral Compression Fractures

Start date: January 2011
Phase: N/A
Study type: Observational

The purpose of this study is to 1. Assess bone marrow edema within the VCF by use of a DE CT virtual noncalcium image compared with MR imaging as standard reference. 2. Evaluate parameters related to the BME of the collapsed vertebral body on DE CT virtual noncalcium images, such as the morphologic signs, visual qualitative detection, and quantitative values.

NCT ID: NCT01249898 Recruiting - Scaphoid Fractures Clinical Trials

The Treatment and Intra-operative Imaging of Scaphoid Fracture Reduction and Fixation

Start date: n/a
Phase: N/A
Study type: Observational

Scaphoid fractures are the most common carpal bone fractures, and second most common wrist fractures (second to distal radius fractures). Lack of proper immobilization or displacement of these fractures commonly results in fracture nonunion or malunion followed by the development of wrist post-traumatic osteoarthritis. In addition, proper reduction and fixation of these fractures are challenging to the most experienced hand surgeons. The investigators are going to follow-up the patients population suffering from Scaphoid fractures(nonunion included) for one year. The investigators will evaluate this follow up results in two ways: 1. Intra-operative imaging of scaphoid fracture fixation - feasibility evaluation. 2. Treatment of scaphoid fracture non-union.

NCT ID: NCT01232426 Recruiting - Mallet Fracture Clinical Trials

A Randomized Controlled Trial of the Treatment of Mallet Fractures

Start date: March 2011
Phase: N/A
Study type: Interventional

Intra-articular fractures at the dorsal base of the distal phalanx of the hand are usually referred to as Mallet fractures. Treatment of Mallet fractures remains controversial. Although no differences in clinical results are reported between conservative treatment and operative treatment, operative treatment is suggested for fractures involving more than 30% of articular surface. There are many different operative techniques, all with specific disadvantages. The investigators hypothesis is that operative treatment of Mallet fractures with one Meniscus Arrow® has a better outcome than conservative treatment with a Mallet splint.

NCT ID: NCT01181037 Recruiting - Clinical trials for Displaced Subcapital Femoral Fracture

Bipolar H.A Versus Trochanteric Antegrade Nail for Treatment of Displaced Subcapital Femoral Fractures

Start date: June 2010
Phase: N/A
Study type: Observational

A retrospective study to compare clinical results of patients that were treated by Bipolar H.A. vs. closed reduction and internal fixation with Trochanteric Antegrade Nail for displaced femoral subcapital fracture.

NCT ID: NCT01173744 Recruiting - Clinical trials for Intertrochanteric Femoral Fractures

Comparison of Gamma Nail Versus Dynamic Hip Screw for the Treatment of Unstable Intertrochanteric Fractures

Start date: July 2010
Phase: N/A
Study type: Interventional

The objective of the study is to examine the treatment of unstable Intertrochanteric fractures with the short Gamma nail, compared to the use of the dynamic hip screw (DHS). This is a prospective study. Sixty patients with unstable Intertrochanteric fractures will be randomized to be treated using either Gamma nail or DHS. The patients will be followed for 12 months. The primary endpoint is the clinical outcome as measured by the Merle d'Aubigne and Postelhip score.

NCT ID: NCT01173081 Recruiting - Fractures Clinical Trials

The Use of Teriparatide as an Adjunctive Therapy for the Treatment of Jones Fractures

Start date: July 2010
Phase: Phase 4
Study type: Interventional

This randomized, placebo-controlled study will evaluate the effectiveness of the adjunctive use of teriparatide for the healing of Jones fractures.

NCT ID: NCT01127776 Recruiting - Clinical trials for Bi-trimalleolar Fracture of Ankle

Bi-trimalleolar Fracture and APOS System Treatment

APOS-IL 001
Start date: October 2010
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate of functional tests and clinical findings with APOS System treatment in patient after bi-trimalleolar fracture of ankle. These functional changes will be evaluated AOFS, FAOS, SF36 and WOMAC scores, walking laboratory GAITRite and clinical examination.