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Foot Ulcer clinical trials

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NCT ID: NCT01921491 Completed - Diabetic Foot Ulcer Clinical Trials

DHACM vs Other Commercially Available Treatments

Start date: August 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether dehydrated human amnion/chorion membrane (dHACM) is more effective than another commercially available product or conservative measures alone when used to treat diabetic foot ulcers (DFUs).

NCT ID: NCT01912092 Completed - Clinical trials for Diabetic Foot Ulcer (DFU)

Askina Calgitrol Paste Diabetic Foot Ulcers

Start date: April 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the efficacy of Askina® Calgitrol® Paste in reducing local infection in subjects treated for mildly infected Diabetic Foot Ulcers (DFU) with Askina® Calgitrol® Paste.

NCT ID: NCT01898923 Completed - Diabetic Foot Clinical Trials

Evaluate the Efficacy and Safety of ON101 Cream for the Treatment of Chronic Diabetic Foot Ulcers

Start date: November 23, 2012
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to evaluate the efficacy of the new treatment of WH-1 ointment compared to Aquacel® Hydrofiber® dressing, applied to chronic diabetic foot ulcers for up to 16 weeks.An additional objective of this study is to collect safety information including adverse events and clinical laboratory abnormalities.

NCT ID: NCT01844479 Completed - Diabetic Foot Ulcer Clinical Trials

Multi-layer Insoles for a Patient-specific Approach to Shear and Pressure Reduction in Diabetes-related Foot Ulcer

Start date: December 2012
Phase: N/A
Study type: Interventional

In this pilot study, the first objective is to bench test a novel shear reducing insole and compare it to current standard insoles and shoes. The second objective is to study twenty-seven insensate diabetes patients with pre-ulcerative foot callus to examine for changes in spatial temporal gait including gait initiation, risk of falling, static and dynamic balance, and plantar temperature response to walking and consecutive plantar stress in both footwear conditions.

NCT ID: NCT01835379 Completed - Diabetic Foot Ulcer Clinical Trials

Study of Oasis Ultra in Diabetic Foot Ulcers

Start date: May 2013
Phase: Phase 4
Study type: Interventional

Many people with diabetes will develop a non-healing diabetic foot ulcer. Many ways are available to try to get a diabetic foot ulcer to heal, including application of Oasis Ultra. The hypothesis to be tested is that application of Oasis Ultra will cause more diabetic foot ulcers to heal than wounds treated with regular medical care. Subjects will have their diabetic foot wounds treated for up to 12 weeks with Oasis Ultra or regular medical care .

NCT ID: NCT01831804 Completed - Wound Healing Clinical Trials

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Single and Repeated Doses of Topical GSK1278863

Start date: June 17, 2013
Phase: Phase 1
Study type: Interventional

This is a randomized, placebo-controlled, single-blind (subjects and investigators will be blinded, GSK internal personnel will not be blinded), parallel-group, two part (Part A, Part B) trial in healthy volunteers and subjects with diabetic foot ulcers. Part A is designed to evaluate single applications of GSK1278863 in one cohort of healthy volunteers (intact skin) and approximately 3 cohorts of diabetic subjects. Part B is designed to evaluate first single, and then repeat applications of GSK1278863 in diabetics, both in the clinic and by subjects at home. Part B will include approximately 3 cohorts in which the concentration of drug applied will be determined by pharmacokinetic data from Part A and earlier cohorts in Part B.

NCT ID: NCT01814267 Completed - Diabetes Clinical Trials

Medico-economical Assessment of Telemedicine During Chronic Diabetes-related Foot Wound Management

AIRPEDIA
Start date: March 2013
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of the study is to assess the cost-effectiveness of telemedicine in the care of chronic diabetic foot ulcers. Patients will be randomized into 2 groups: 1/conventional care group with iterative visits to diabetes specialist or 2/innovative care (telemedicine group). the health insurance system perspective is adopted.

NCT ID: NCT01813305 Completed - Diabetes Mellitus Clinical Trials

CSTC1 for Diabetic Foot Ulcers Phase II Study

Start date: July 9, 2014
Phase: Phase 2
Study type: Interventional

The objective of this study is to evaluate the efficacy and safety of CSTC1 in patient with diabetic foot ulcers.

NCT ID: NCT01731808 Completed - Diabetic Foot Ulcer Clinical Trials

Outpatient Nurse Managed Counseling Program for Patients With Diabetic Foot Ulceration: a Pilot Study

Start date: October 2010
Phase: N/A
Study type: Interventional

The purpose of the study is to evaluate the feasibility and effectiveness of a physician directed nurse managed earlier outpatient counselling intervention for patients with diabetic foot ulceration. For the purpose effectiveness is defined in two ways.1) as a reduction in hospital readmissions for complication for foot ulcers such as amputation or increased severity of the ulcer and 2) reduction in amputations, readmission rates. Selected covariates (self-efficacy,self-management, social support and depression) will be included to estimate predictors for readmission and amputation.

NCT ID: NCT01699100 Completed - Clinical trials for Foot Ulcer, Diabetic

Reduction of Plantar Pressure in Neuropathic Diabetic Foot Patients Using Insoles With Removable Pegs Design

Start date: September 2011
Phase: N/A
Study type: Interventional

The purpose of this study was to determine if insoles with removable pegs could effectively reduce the plantar aspect pressure with the aid of in-shoe plantar pressure analysis for guidance of peg removal.