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Folate Deficiency clinical trials

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NCT ID: NCT05792241 Completed - Iodine Deficiency Clinical Trials

Acceptability and Nutritional Impact of Double-fortified Salt Containing Iodine and Folic Acid - Phase 1

DFS-IoFA-1
Start date: June 26, 2023
Phase:
Study type: Observational

The overarching objective of this two-phase project is to assess the effects of fortifying iodized salt with folic acid on improving women's folate status and thereby reduce the risk of neural tube defects (NTDs), which are highly prevalent in Ethiopia. The project will be conducted in two phases. The purpose of Phase 1, described herein, is to complete formative research in preparation for a community-based, randomized trial, which will be carried out in Phase 2. The objectives of Phase 1 are to: 1) assess the hematological condition and nutritional status with respect to folate, iodine, and other micronutrients among non-pregnant women of reproductive age (WRA) in the study communities, and 2) measure discretionary salt and dietary folate intakes of the women and their households.

NCT ID: NCT05453708 Completed - Clinical trials for Autism Spectrum Disorder

Maternal Risk Factors for Autism Spectrum Disorders: A Case-Control Approach

Start date: June 16, 2022
Phase:
Study type: Observational

New research suggests that about 1 in 8 children may be diagnosed with an autism spectrum disorder (ASD) in the United States. This could be due to several reasons which remain unknown. This study invites mothers who have given birth to children in the United States to share their experiences with diet and supplementation during pregnancy. The purpose of this study is to understand the role of a mother's diet, social standing, and supplementation with folate or folic acid may have on her child's future development of autism. Comparisons will be made between mothers of children who have a child with an official ASD diagnosis from a clinician to mothers of children without an ASD diagnosis. Findings from this study can be used to help identify risk factors for ASD risk.

NCT ID: NCT04632771 Completed - Anemia Clinical Trials

Nutritional Status and Bouillon Use in Northern Ghana

Start date: October 19, 2020
Phase:
Study type: Observational

This pilot aims to generate data that are critical for informing the design of a planned, more detailed study to evaluate the effect of multiple micronutrient (MN)-fortified bouillon cube on biomarkers of nutrient status of women and children. Data collection includes measures of nutritional status and dietary intake among women and children and their households in communities in northern Ghana.

NCT ID: NCT03489538 Completed - Clinical trials for Bariatric Surgery Candidate

Homocysteine After Laparoscopic Roux-enY Gastric Bypass

Start date: April 9, 2013
Phase:
Study type: Observational

Changes in homocysteine values after bariatric surgery remain controversially discussed. This is the first comprehensive summary to depict timeline changes in homocysteine levels following laparoscopic roux-en-Y gastric bypass.

NCT ID: NCT03376490 Completed - Clinical trials for Vitamin D Deficiency

Study of the Association of Muscle Strength, Balance and Other Factors With Vitamin Levels Among Elderly Diabetics

Start date: January 1, 2012
Phase: N/A
Study type: Observational

Vitamin B12 deficiency can cause severe problems with the blood, nerves, brain and psychological well-being. Ironically, our modern methods for the control of diabetes mellitus can actually contribute to vitamin B12 deficiency. This is because the diabetic medication "metformin", low-cholesterol diets lacking in meats (a natural source of vitamin B12) and the use of powerful anti-gastric medication can all reduce the natural absorption of vitamin B12 from the diet, especially in elderly people with diabetes. There is both a high prevalence of vitamin B12 deficiencies and falls among the elderly with type 2 diabetes mellitus and the investigators hypothesize that B12 deficiency contributes directly and significantly to falls in elderly diabetics through impaired muscle strength, gait and balance. This study therefore proposes to investigate the association between vitamin B12 deficiency and fall risk among diabetic elderly patients (older than 65 years) in the polyclinic setting by assessing muscle strength, balance and walking speed. The predictors of vitamin B12, folate, homocysteine and vitamin D levels will also be explored in this study. If the hypothesis is right, this would be of public health importance & can lead to further studies that can change the way we treat diabetes by reducing falls in our elderly diabetics through the screening for, prevention and treatment of B12 deficiency.

NCT ID: NCT03089684 Completed - Folate Deficiency Clinical Trials

Correspondence of Folate Dietary Intake and Biomarker Data

Start date: January 1, 2011
Phase: N/A
Study type: Observational

This NHANES analysis compares self-reported dietary folate with serum and red blood cell folate status in U.S. adults.