Fluid Overload Clinical Trial
— AHMOfficial title:
Advanced Hemodynamic Monitoring in Free Flap Surgery
Verified date | May 2017 |
Source | Universitätsklinikum Hamburg-Eppendorf |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Background: Anesthesia in free flap surgery is challenging. Monitoring of hemodynamic
changes and their influence on the cardiovascular system in permanent feedback loops allow
control, which is what anesthesiologists aim for to ensure an adequate blood flow and tissue
oxygenation. The circulatory support and inferable volume administration are managed via
heart rate (HR) and mean arterial pressure (MAP), but both parameters are influenced by
variable components and are thus unfavorable for volume management. The aim of this study
was to evaluate whether volume requirement may be assumable to additional monitoring
parameters.
Methods: 31 patients were enrolled prospectively. HR, MAP, central venous pressure and O2
saturation were comprehended based on the protocols. We expanded the data set by a permanent
blinded intraoperative monitoring with registration of the Cardiac Index (CI) and Stroke
Volume Variation (SVV) and semi-invasive pulse-contour analysis utilizing the
Pro-AQT-Device.
Status | Completed |
Enrollment | 31 |
Est. completion date | December 2014 |
Est. primary completion date | December 2014 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - 18 years of age, free flap surgery, oral squamous cell carcinoma, informed consent Exclusion Criteria: - <18 years of age, no informed consent |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Universitätsklinikum Hamburg-Eppendorf |
Wakeling HG, McFall MR, Jenkins CS, Woods WG, Miles WF, Barclay GR, Fleming SC. Intraoperative oesophageal Doppler guided fluid management shortens postoperative hospital stay after major bowel surgery. Br J Anaesth. 2005 Nov;95(5):634-42. Epub 2005 Sep 9. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Stroke Volume Variance (SVV) | during the surgical intervention | ||
Secondary | Mean arterial pressure | during the surgical intervention | ||
Secondary | heart rate | during the surgical intervention | ||
Secondary | cardiac index | during the surgical intervention | ||
Secondary | standard resistance index | during the surgical intervention |
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