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Fissure in Ano clinical trials

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NCT ID: NCT03855046 Recruiting - Fissure in Ano Clinical Trials

Complex Treatment of a Chronic Anal Fissure

Start date: September 1, 2019
Phase: Phase 4
Study type: Interventional

This study is aimed at studying the efficacy and safety of treating chronic anal fissure with botulinum toxin versus lateral subcutaneous sphincterotomy.

NCT ID: NCT03787030 Completed - Pain Clinical Trials

Application of Vitamin E on Anal Fissure

Start date: December 21, 2018
Phase: Phase 3
Study type: Interventional

Patients were randomized into 2 groups: - Vitamin E: Vitamin E ointment will be applied during 8 weeks - Nitroglycerin: Nitroglycerin ointment will be applied during 8 weeks Healing rate of chronic anal fissure in patients receiving Nitroglycerin ointment and subjects patients receiving Vitamin E ointment were evaluated .

NCT ID: NCT03780998 Not yet recruiting - Hemorrhoids Clinical Trials

Effects of Sodium Pentaborat Based Gel on Perianal Benign Diseases

Start date: January 1, 2019
Phase:
Study type: Observational

New produced and patented sodium pantaborat based gel will be use for treatment of benign perianal diseases (hemooroidal disease, anal fissura anda perianal fistula)

NCT ID: NCT03554421 Completed - Clinical trials for Chronic Anal Fissure

Percutaneous Tibial Nerve Stimulation - an Alternative Treatment Option for Chronic Therapy Resistant Anal Fissure

Start date: September 30, 2013
Phase: N/A
Study type: Interventional

At a tertiary referral centre, 10 patients (4 male and 6 female; mean age 49.8 years) were given neuromodulation via the posterior tibial nerve to the sacral nerve for 30 min on 10 consecutive days. All patients had failed conventional medical treatment. The visual analogue scale (VAS), St. Marks score, Wexner`s constipation score, Brief Pain Inventory (BPI - SF), bleeding and mucosal healing were evaluated before treatment, at termination, after 3 months and then yearly during three years.

NCT ID: NCT03528772 Completed - Anal Fissure Clinical Trials

Topical Minoxidil Versus Topical Glyceryl Trinitrate in Treatment of Chronic Anal Fissure

Start date: May 10, 2018
Phase: N/A
Study type: Interventional

This randomized trial aims to compare two topical treatments in the treatment of chronic anal fissure: minoxidil gel and glycreyl trintrate cream. The endpoint of the study is the duration of healing of anal fissure whereas secondary endpoints include adverse effects of each treatment and recurrence of anal fissure

NCT ID: NCT03426449 Completed - Anal Fissure Clinical Trials

Posterolateral Versus Lateral Internal Anal Sphincterotomy for Chronic Anal Fissure

Start date: January 1, 2015
Phase: N/A
Study type: Interventional

The present study aimed to compare the standard lateral internal sphincterotomy at 3 o'clock with posterolateral internal sphincterotomy at 5 o'clock in regards healing time, postoperative recurrence and complications, particularly fecal incontinence.

NCT ID: NCT03405922 Completed - Hemorrhoids Clinical Trials

Perianal Nerval Block in Proctological Interventions

Start date: February 1, 2018
Phase: Phase 4
Study type: Interventional

The aim of this study is to evaluate whether a local perianal block performed during a proctological intervention can reduce the postoperative pain.

NCT ID: NCT03355846 Completed - Acute Anal Fissure Clinical Trials

Pain and Bleeding in Subjects With Acute Anal Fissure: Comparative Evaluation of Three Treatments

PBSAAF
Start date: May 1, 2018
Phase: Phase 4
Study type: Interventional

Starting from the observation that acute anal fissure (AAF) in 6-8 weeks can heal spontaneously and that some of the commonly used commercial products in clinical practice would seem to be useful, the rationale of the comparative study is to try to identify, in compliance with the protocol of Helsinki (2013), the most effective short-term treatment for the disappearance of pain in defecation and cessation of bleeding, shortening the duration of the healing process and favoring the patient's rapid return to his / her activity, respect for patient safety.

NCT ID: NCT03345511 Completed - Pain, Postoperative Clinical Trials

Ultrasound Guided Caudal Block for Benign Anal Surgery

Start date: November 1, 2015
Phase: N/A
Study type: Interventional

Interventional study that evaluate analgesia and side effects of Ultrasound guided Caudal block preoperatively in benign canal anal surgery

NCT ID: NCT03105674 Withdrawn - Hemorrhoids Clinical Trials

Multi-Drug Analgesia vs. Standard Solution for Anal Surgery

Start date: May 1, 2017
Phase: Phase 4
Study type: Interventional

The primary aim is to test the magnitude and duration of analgesia provided by single dose multi-drug analgesia administered for perianal block, and compare with standard solution (Marcaine & Lidocaine in 1:1 mixture - Total 60 ml), at post-operative period and also to compare with the standard solution including their respective post-operative opioid or non-opioid oral analgesic requirement. Local anesthesia via a perianal block using multi-drug analgesia or standard solution will be compared using the Numeric pain rating scale on Post-operative day 1, 3 and during follow up visit on day 7. The investigators hope to find a better control of post-operative analgesia which will lead to better functional outcomes. Possible decrease consumption of opioids in the post-operative period will perhaps decrease the cost and chances of addiction and will increase patient comfort and compliance.