Clinical Trials Logo

Clinical Trial Summary

This study will compare a 12-session behavioral activation (BA) intervention modified for first-episode psychosis (FEP) to usual community mental health care (i.e., treatment-as-usual; TAU) delivered over 6 months with a sample of Latinos with FEP and their families. Comparable family group sessions will also be delivered to participants in both conditions. It is expected that BA participants will show better engagement than TAU participants.


Clinical Trial Description

After an initial pre-screen, screening, and pre-intervention assessment, enrolled participants will be randomized to either BA or TAU. The study intervention phase will last up to 6 months, during which time BA participants will receive up to 12 one-on-one BA sessions and TAU participants will receive the usual care (e.g., medication management and any other service [e.g., group counseling]). Participants will be assessed at post-intervention, 1-month-post-intervention, and 6-month-post-intervention. The primary objective of aim 1 is to examine whether BA for FEP improves engagement in services better than TAU among Latinos with FEP and their families. Secondary objectives of aim 1 are to examine whether BA participants show greater improvements in quality of life, symptoms (e.g., psychosis, depression), functioning, and recovery compared to TAU participants, and whether BA participants have greater remission rates than the TAU group at 1- and 6-month post-intervention. Additionally, the association between potential BA mediators and engagement will be examined to identify mechanisms of engagement. Potential predictors of engagement will also be examined. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05310838
Study type Interventional
Source California State University, San Bernardino
Contact Maria Santos, PhD
Phone 909-537-4507
Email Maria.Santos@csusb.edu
Status Recruiting
Phase N/A
Start date March 1, 2022
Completion date February 28, 2026

See also
  Status Clinical Trial Phase
Recruiting NCT04298450 - ED to EPI: Using SMS to Improve the Transition From the Emergency Department to Early Psychosis Intervention N/A
Completed NCT00202280 - Efficacy of Treating First Episode Psychosis With Folic Acid,B12 and B6 in Addition to Antipsychotic Medication Phase 2/Phase 3
Completed NCT01026584 - Efficacy and Safety of Aripiprazole in First Episode Psychosis Phase 4
Completed NCT03983421 - Feasibility of an Early Detection Program for Early Psychosis on a College Campus
Recruiting NCT04046497 - Artificial Intelligence to Measure Adherence to Oral Medication Phase 4
Withdrawn NCT04369677 - Thermoregulation Among Individuals With First-episode Psychosis
Completed NCT03568500 - A Trial to Explore Acceptance and Performance of Using a Digital Medicine System With Healthcare Professionals and Adults With Schizophrenia, Schizoaffective Disorder, or First Episode Psychosis on an Oral Atypical Antipsychotic Phase 4
Completed NCT03102151 - Reducing the Duration of Untreated Psychosis
Completed NCT00916461 - Role of Minocycline in First Episode Psychosis Phase 1/Phase 2
Completed NCT03501160 - Socially Inappropriate Behaviour in People With First Episode Psychosis: A Caregivers' Perspective
Recruiting NCT03196128 - Early Intervention Psychosis Communication and Engagement Trial N/A
Recruiting NCT04005378 - Disengagement in CSC: Identifying Those at Risk and Addressing Their Needs Phase 4
Recruiting NCT03919760 - Early Psychosis Intervention - Spreading Evidence-based Treatment
Completed NCT03409393 - Feasibility and Relevance of High-Intensity Functional Training in Patients With First-Episode Psychosis N/A
Completed NCT01753284 - First Episode Psychosis and Pathway to Care in Nordland
Completed NCT01157585 - Efficacy and Safety of Paliperidone ER in First Episode Psychosis Phase 4
Completed NCT05737966 - Evaluation of Case Management for First Episode Psychosis Using the PEPsy-CM Checklist
Recruiting NCT04021719 - OnTrackNY's Learning Healthcare System
Recruiting NCT04889911 - Pilot RCT of Self-stigma Treatment for First Episode Psychosis N/A
Recruiting NCT04853485 - Repetitive Transcranial Magnetic Stimulation in Early Psychosis and The Functional Connectivity Biotypes N/A