Clinical Trial Details
— Status: Completed
Administrative data
NCT number |
NCT03478267 |
Other study ID # |
0584-16-RMB |
Secondary ID |
|
Status |
Completed |
Phase |
|
First received |
|
Last updated |
|
Start date |
February 17, 2019 |
Est. completion date |
March 1, 2021 |
Study information
Verified date |
May 2022 |
Source |
Rambam Health Care Campus |
Contact |
n/a |
Is FDA regulated |
No |
Health authority |
|
Study type |
Observational [Patient Registry]
|
Clinical Trial Summary
Pregnant women between 32-41 weeks' gestation designated for either vaginal birth or cesarean
section will be recruited for the study. Data regarding maternal resting heart rate and fetal
baseline heart rate as depicted on the monitor will be collected. A blood sample will be
acquired from the parturient and the umbilical cord as well as a sample from the placenta
will be obtained. Levels of Acetyl Choline Esterase (AChE) will be determined from all
aforementioned samples. Statistical correlation between fetal baseline heart rate and fetal
and maternal AChE levels will be assessed.
Description:
Pregnant women between 32-41 weeks' gestation designated for either vaginal birth or cesarean
section will be recruited for the study. After signing an informed consent, data regarding
maternal resting heart rate and fetal baseline heart rate as depicted on the monitor will be
collected.
Patients will be divided into 2 equal groups according to fetal baseline heart rate:
1. st group-fetal heart rate between 110-130 beats per minute (bpm).
2. nd group-fetal heart rate between 140-160 bpm. A blood sample will be acquired from the
parturient and the umbilical cord as well as a sample from the placenta will be
obtained. Levels of Acetyl Choline Esterase (AChE) will be determined from all
aforementioned samples. Statistical correlation between fetal baseline heart rate and
fetal and maternal AChE levels will be assessed.
Data regarding demographic, medical and obstetric information of the participants will be
obtained from the hospital's electronic records.