Predictive Value of ProCalcitonin for the Detection of Bacteraemia in Patients Presenting to the Emergency Department for Low Risk Chemo-induced Febrile Neutropenia — CALIF  

Febrile Neutropenia, Drug-Induced Clinical Trial

Official title: Predictive Value of ProCalcitonin for the Detection of Bacteraemia in Patients Presenting to the Emergency Department for Low Risk Chemo-induced Febrile Neutropenia According to the MASCC Score: a Prospective, Monocentric Observational Study (CALIF)

Status Terminated

Clinical Trial Summary

CALIF study is a monocentric observational study which aim is to analyse the value of adding procalcitonin (PCT, a pre-hormon increased in bacterial infection and septicaemia) in the management of chemo-induced febrile neutropenia occurring in patient with solid tumour. Febrile neutropenia will be managed according to international guidelines. PCT will be dosed at initial presentation. Primary objective is to determine the optimal value of PCT for the detection of septicaemia in low risk (according to MASCC score). The investigators plan also to compare two risk stratification scores: the validated MASCC score and a recently developed score which includes PCT and other more objective items.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Bacteremia
• Chemotherapy-Induced Febrile Neutropenia
• Emergencies
• Febrile Neutropenia
• Febrile Neutropenia, Drug-Induced
• Fever
• Hyperthermia
• Neutropenia

• NCT number: NCT03182465
• Study type: Interventional
• Source: Cliniques universitaires Saint-Luc- Université Catholique de Louvain
• Status: Terminated
• Phase: N/A
• Start date: October 4, 2017
• Completion date: December 25, 2022