Fatigue Clinical Trial
— SFNROfficial title:
Swiss Frailty Network and Repository
Verified date | May 2023 |
Source | University of Zurich |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational [Patient Registry] |
Physical frailty is an age-related medical syndrome defined by a decline in multiple body systems, thus causing increased vulnerability, even in the face of minor stressors (1) It has been linked to multiple negative health outcomes, including extended length of stay in acute care due to complications, hospital re-admissions, and mortality among older patients. About 10-30% of community-dwelling seniors are considered frail(2) with an additional 40% being at risk for the condition (pre-frailty). By 2030, the number of older adults with frailty is expected to at least double, in parallel to the projected growth of the older segment of the population. Frail seniors consume 3-times more health care resources then their robust counterparts. Thus, the health economic impact of frailty is expected to be enormous and a call to action has been posed. Big data in healthcare provides important opportunities for the identification of frailty among the growing number of older patients. This is relevant as frailty is considered a better predictor of adverse outcomes than chronological age alone. Therefore, several medical specialties have started to assess frailty in cancer patients, heart surgery candidates and potential organ transplant recipients.
Status | Active, not recruiting |
Enrollment | 1500 |
Est. completion date | February 28, 2024 |
Est. primary completion date | May 30, 2023 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 65 Years and older |
Eligibility | Inclusion Criteria: - Men and women age 65 and older - Admission as inpatients to acute care at any partnering university hospital (eFI - subgroup) - Admission as inpatients to acute geriatric care (cFI - subgroup) - Patients or proxies need to provide a written informed consent (geriatric patients (cFI and eFI): project consent; non-geriatric patients ((eFI): general consent) Exclusion Criteria: - Documented objection of participating in the project and/or subsequent use of personal health data - Not fluent in local language (i.e. German, French) - Patient is uncooperative or presence of inability to perform functional tests due to severe cognitive and/or physical impairment/acute medical illness |
Country | Name | City | State |
---|---|---|---|
Switzerland | Dept. of Geriatrics and Aging Research, University of Zurich / Geriatric Clinic University Hospital Zurich | Zürich | ZH |
Lead Sponsor | Collaborator |
---|---|
University of Zurich | University Department of Geriatric Medicine FELIX PLATTER, University Hospital Inselspital, Berne, University Hospital, Geneva, University of Lausanne Hospitals |
Switzerland,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Positive and negative predictive value of the eFI | Validation Study | year 2-3 | |
Primary | sensitivity and specificity of the eFI | Validation Study | year 2-3 | |
Primary | The correlation between the cFI and the eFI with length of stay and in-hospital mortality | Correlation Study | year 2-3 |
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