Effect of Antioxidant on Endurance Performance in Healthy Men

Status Completed

Clinical Trial Summary

oligomerized litchi fruit extract may enhance the submaximal endurance exercise performance

Clinical Trial Description

Regular physical exercise has many beneficial effects, but it has been reported that strenuous exercise could elevate the production of free radical and other reactive oxygen species (ROS) which eventually injure the tissues and decrease the muscle function.So many kinds of antioxidant supplementations have been tried to decrease the muscle fatigue and enhance the exercise performance. polyphenolic flavonoids abundant in fruits and leafy vegetables have strong antioxidant effect. oligomerized litchi fruit extract has strong antioxidant capacity and higher bioavailability compared to that of grape seed polyphenol. The aim of this study was to determine whether oligomerized litchi fruit extract could induce endurance exercise performance more than Vit C + Vit E mixture or placebo could do. Therefore, we designed double blind randomized controlled trial, setting the change of running time to exhaustion under submaximal treadmill test as the primary endpoint. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

Exercise Tolerance

Clinical Trial Details

NCT number	NCT00731926
Study type	Interventional
Source	Seoul National University Hospital
Contact
Status	Completed
Phase	Phase 2/Phase 3
Start date	September 2007
Completion date	February 2008

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