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Esophagus Cancer clinical trials

View clinical trials related to Esophagus Cancer.

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NCT ID: NCT06147180 Not yet recruiting - Quality of Life Clinical Trials

Comparison of Long-term Survival and Quality of Life After Minimally Invasive Esophagectomy Versus Open Esophagectomy

Start date: November 27, 2023
Phase:
Study type: Observational

To analyze and compare the long-term recurrence-free survival rate, overall survival rate and quality of survival after minimally invasive esophagectomy and open esophagectomy, and to conduct subgroup analysis according to the type of esophageal cancer and pathological stage, etc., and to explore more deeply the differences between minimally invasive esophagectomy and open esophagectomy in terms of the benefits for different types of patients, so as to provide reference for the selection of the clinical surgical methods. We will also use the available data to analyze the influence of other factors on patients' long-term survival after surgery.

NCT ID: NCT06097078 Not yet recruiting - Esophageal Cancer Clinical Trials

Endoluminal Vacuum Therapy to Prevent Anastomotic Leakage After Esophagectomy Due to Esophageal Cancer

ESPY
Start date: June 2024
Phase:
Study type: Observational

A prospective, multi-centre, exploratory and observational one-arm study to evaluate preventive Endoluminal Vacuum Therapy(pEVT) to prevent anastomotic leakage after esophagectomy due to esophageal cancer. The main objective is to evaluate the potential protective effect of prophylactic preemptive endoluminal vacuum therapy on esophageal-gastric anastomosis dehiscence after esophagectomy.

NCT ID: NCT06036563 Not yet recruiting - Breast Cancer Clinical Trials

Prospective Screening and Differentiating Common Cancers Using Peripheral Blood Cell-Free DNA Sequencing

Start date: September 2023
Phase:
Study type: Observational [Patient Registry]

The goal of this observational study is to screen and differentiate common cancers in participants with or without suspicious lesions. The main question the investigators aim to answer is: Can the developed model, using peripheral blood cell-free DNA sequencing, work well in screening and classifying common cancers especially in the early stages? Participants will undergo the collection of 15~20ml of blood and 1~2 telephone follow-up calls.

NCT ID: NCT05174117 Not yet recruiting - Esophagus Cancer Clinical Trials

Influence of Different Light Dose on the Adverse Effect of Swallowing for Esophageal Carcinoma

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

The purpose of this experiment is to study the alleviating effects and side effects of different laser irradiation doses on esophageal stricture of esophageal cancer in order to find the appropriate dose of light.

NCT ID: NCT05023928 Not yet recruiting - Carcinoma Clinical Trials

Tumor Antigen-sensitized DC Vaccine as an Adjuvant Therapy for Esophagus Cancer

Start date: September 1, 2021
Phase: Phase 1
Study type: Interventional

The aim of this single center, single arm and prospective study is to explore the safety and efficacy of tumor antigen-sensitized DC vaccine in postoperative adjuvant treatment of esophageal cancer.

NCT ID: NCT02961140 Not yet recruiting - Anesthesia Clinical Trials

Different Anesthetic Managements of Esophageal Resection and Reconstruction

Start date: November 2016
Phase: N/A
Study type: Interventional

Anesthetic management and fluid therapy is crucial in esophageal resection and reconstruction, which is associated with high incidence of postoperative morbidity and mortality. This study aims to investigate the effect of goal directed fluid management on the postoperative outcome of esophageal resection and reconstruction.

NCT ID: NCT02607826 Not yet recruiting - Colorectal Cancer Clinical Trials

Short-term Starvation vs. Normal Diet Before Chemotherapy of Solid Tumors

Start date: November 2016
Phase: N/A
Study type: Interventional

Recent pre-clinical data provide strong evidence that short-term starvation before the administration of cytostatic drugs for the chemotherapy of solid tumors leads to significantly higher efficacy and lower toxicity levels. However, these findings have so far not been validated in patients. The aim of this trial is to provide first clinical evidence regarding the impact of pre-chemotherapeutic short-term starvation on response to therapy (primary endpoint). Additionally, progression-free survival, adverse events, and overall survival will be monitored (secondary endpoints). In perspective, short-term starvation before chemotherapy could represent a simple and secure way to improve both efficacy and tolerance of chemotherapies at low cost.