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Erectile Dysfunction clinical trials

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NCT ID: NCT04349059 Recruiting - Clinical trials for Erectile Dysfunction

The Impact of Dietary Pattern on Erectile Function

ERECTION
Start date: October 30, 2023
Phase: N/A
Study type: Interventional

The goal of this study is to determine whether erectile function is impacted by dietary patterns in healthy men with normal erectile function.

NCT ID: NCT04345965 Recruiting - Clinical trials for Erectile Dysfunction

Sirolimus Eluting Balloon Utilization for Treatment of Vasculogenic Erectile Dysfunction

SUASION
Start date: September 1, 2019
Phase:
Study type: Observational

Brief Summary: Background and pathophysiology: Erectile dysfunction (ED) is defined as the recurrent inability to achieve and maintain an erection satisfactory for sexual intercourse. ED is not in itself a "serious" disease, but its impact on quality of life is extremely important, affecting the family and interpersonal relationships. Male erection is a complex mechanism that involves neuro-vascular tissue responses with several phases including arterial dilatation, smooth muscle cells relaxation and ultimately veno-occlusive activation. Vasculogenic erectile dysfunction can be divided in arteriogenic (when there is insufficiency of arterial component of erection due to atherosclerotic plaque encroachment of the penile arteries) or venogenic (where there is insufficiency of the venous component of erection for venous endoleak) Standard treatment Erectile dysfunction is commonly treated by oral phosphodiesterase-5-inhibitor (PDE5i) administration. However, up to 50% of men have a suboptimal response to PDE5-i therapy with the need of additional therapies. New treatment Only recently several studies have been published on percutaneous treatment of ED using plain old balloon angioplasty (POBA), Drug eluting balloons (both paclitaxel and sirolimus, PEB and SES) and drug eluting stents (DES). Aim of the study: Evaluation of the safety and feasibility of sirolimus drug eluting balloon treatment in focal atherosclerotic lesions of the internal pudendal arteries among men with erectile dysfunction (ED) and a no response to phosphodiesterase-5 inhibitors.

NCT ID: NCT04341025 Recruiting - Clinical trials for Situational Erectile Dysfunction

Providing Insight Into and Mindfulness for Situational Erectile Dysfunction

PRIMED
Start date: April 14, 2020
Phase: N/A
Study type: Interventional

Erectile dysfunction (ED) is among the most common sexual dysfunctions experienced by men, affecting at least one third of men across the lifespan. Although pharmacological treatments are available, adherence to these treatments is poor, suggesting the need for integration of psychological interventions. This study will determine if a 6-session mindfulness-based psychosexual therapy (MBPST) group will be effective and feasible for men with situational ED. This study is adapted from a previously published 4-session MBPST protocol which was found to be beneficial for men with situational ED. Outcomes are measured using self-report questionnaires on sexual functioning/enjoyment, relationship satisfaction, and treatment acceptability.

NCT ID: NCT04338087 Completed - Clinical trials for Erectile Dysfunction

The Effect of Assisted Reproductive Technology on Male Sexual Function.

Start date: January 1, 2017
Phase:
Study type: Observational

Men participating in assisted reproductive technology treatments will be recruited to a study involving filling erectile function questionnaires throughout fertility treatments, pregnancy and up to 1 year after birth.

NCT ID: NCT04333173 Completed - Clinical trials for Erectile Dysfunction

Endovascular Therapy for Erectile Dysfunction

RE-ACTION
Start date: February 1, 2017
Phase:
Study type: Observational

Brief Summary: Background and pathophysiology Erectile dysfunction is a serious disease with a significant impact on the quality of life. Male erection is a complex mechanism that involves neuro-vascular tissue responses with several phases including arterial dilatation, smooth muscle cells relaxation and ultimately veno-occlusive activation. Vasculogenic erectile dysfunction can be divided in arteriogenic (when there is insufficiency of arterial component of erection due to atherosclerotic plaque encroachment of the penile arteries) or venogenic (where there is insufficiency of the venous component of erection for venous endoleak) Standard treatment Erectile dysfunction is commonly treated by oral phosphodiesterase-5-inhbitor (PDE5i) administration. However, up to 50% of men have a suboptimal response to PDE5-i therapy with the need of additional therapies. New treatment Only recently several studies have been published on percutaneous treatment of ED using POBA, Drug eluting balloons (both paclitaxel and sirolimus, PEB and SES) and drug eluting stents (DES). Aim of the study The study was aimed at evaluating both arteriogenic and venogenic endovascular treatments in patients affected by erectile dysfunction in an Italian patient cohort.

NCT ID: NCT04304742 Completed - Painful Hip Clinical Trials

Radiologist Diagnostic Performance Versus Artificial Intelligence (AI)

RAVIA
Start date: March 1, 2020
Phase:
Study type: Observational

In France, femoral neck fracture is mainly detected with interpretation of pelvis/hip X-ray imaging (French Health Authority recommandation). However, up to 10% of fractures are not identified or misdiagnosed, especially in patients admitted to the emergency department. Indeed, radiologists may be subject to excessive work, wich cause the risk of inaccurate on X-rays diagnosis. The Artificial intelligence (AI) begins study the detection of fratures on medical imaging. In this retropective study, this technology developed by GLEAMER company is tested to evaluate the detection rate of hip fracture and specifically femoral neck fracture, compared to the radiologist diagnostic, in eldery patients admitted in emergency department. AI could optimize the diagnostic performance of radiologists (increase of confidence level) and improve the efficiency of suspected fractures sorting from emergency department.

NCT ID: NCT04219462 Recruiting - Clinical trials for Diabetes Mellitus, Type 2

Effect of ESWT on ED in Type 2 Diabetics

Start date: December 2, 2019
Phase: N/A
Study type: Interventional

Diabetes mellitus (DM) is known not only for its widespread prevalence, but also for its significant complications including cerebrovascular disease, coronary artery disease, renal failure, vision loss, and neuropathy. Of particular importance to sexual medicine, diabetes has also been strongly associated with erectile dysfunction (ED).ED is defined as the inability to obtain and/or maintain the erection firm enough to achieve a successful sexual intercourse on a regular basis. It is a more common condition in males with type 2 DM. In the field of sexual medicine numerous studies have shown that extracorporal shock wave therapy (ESWT) is safe, noninvasive, and, most importantly, an effective method for treating vascular ED

NCT ID: NCT04200937 Enrolling by invitation - Clinical trials for Erectile Dysfunction

IT Matters: The Erectile Restoration Registry

It MATTERS
Start date: August 5, 2021
Phase:
Study type: Observational

The primary objective of the It MATTERS registry is to assess erectile function at 6 months, post implantation of an It MATTERS Study Penile Prosthesis, demonstrating an improvement in quality of life from baseline.

NCT ID: NCT04185441 Recruiting - Clinical trials for Erectile Dysfunction

Efficacy and Safety of Tanzânia Association in the Treatment of Erectile Dysfunction Associated With Benign Prostatic Hyperplasia

Start date: March 14, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of Tanzânia association in adults with erectile dysfunction associated with Benign Prostatic Hyperplasia.

NCT ID: NCT04179747 Completed - Clinical trials for Erectile Dysfunction

Psychotherapy and Pharmacotherapy in the Treatment of Erectile Dysfunction: A Pilot Study

Start date: January 18, 2018
Phase: N/A
Study type: Interventional

The study involved the administration of pharmacotherapy and cognitive behavior psychotherapy to individuals suffering from erectile dysfunction. The study was randomized controlled trial with two arms involving a control group. The study was conducted with an aim of pilot and feasibility study to evaluate the efficacy and suitability of cognitive behavior psychotherapy with individuals suffering from erectile dysfunction.