Clinical Trials Logo
  1. Home
  2. Epiretinal Membrane
  3. NCT06232616

Vitrectomy Combined With Intravitreal Dexamethasone Implant for Idiopathic Epiretinal Membrane With Macular Oedema

Epiretinal Membrane Clinical Trial

Official title:
Vitrectomy Combined With Intravitreal Dexamethasone Implant for the Treatment of Idiopathic Epiretinal Membrane With Cystoid Macular Oedema

Clinical Trial Summary

The goal of this clinical trial is to evaluate the efficacy and safety of 25-gauge pars plana vitrectomy combined with intravitreal dexamethasone implant for the treatment of idiopathic epiretinal membrane with cystoid macular oedema. The main questions it aims to answer are: - mean changes in best corrected visual acuity and central macular thickness from baseline to post-operative 24 weeks - mean change in proportion of cystoid macular oedema area from baseline to post-operative 24 weeks - intraocular pressure throughout postoperative 24 weeks - concentrations of inflammatory factors in vitreous samples Participants will undergo a standard three-port 25-gauge pars plana vitrectomy and epiretinal membrane peeling combined with phacoemulsification, aspiration, and intraocular lens implantation. The dexamethasone implant will be injected into the vitreous cavity at the end of the operation.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06232616
Study type Interventional
Source Shanghai Eye Disease Prevention and Treatment Center
Contact
Status Enrolling by invitation
Phase N/A
Start date March 11, 2024
Completion date December 31, 2024
View Details
See also
  Status Clinical Trial Phase
Completed NCT03332758 - Inflammasomes in Cell Death in FTMH, ERM, and RRD
Active, not recruiting NCT04130841 - Effects of Internal Limiting Membrane Peeling on Visual Function in Epiretinal Membrane Surgery N/A
Recruiting NCT03713268 - Intraoperative OCT Guidance of Intraocular Surgery II
Terminated NCT01532765 - Randomized Trial Comparing Epiretinal Membrane Surgery With and Without Internal Limiting Membrane Removal N/A
Completed NCT01474655 - Retinal Layers and Visual Rehabilitation After Epiretinal Membrane Removal N/A
Active, not recruiting NCT04120311 - Episcleral Dexamethasone for Treatment of Macular Edema and Inflammatory Disorders of the Posterior Pole Phase 1
Completed NCT04445142 - Fovea ERM After Fovea-sparing ILM Peeling
Recruiting NCT01701518 - A Pilot Study of the Effectiveness of Intra-operative Ozurdex® in Vitrectomy Surgery for Epiretinal Membranes N/A
Completed NCT01627977 - Association of Lutein, Zeaxanthin and Brilliant Blue in Chromovitrectomy Phase 3
Completed NCT00408720 - Comparison of a Spectral OCT/SLO With the Stratus OCT for Imaging Various Retinal Pathologies N/A
Completed NCT01771939 - Phacoemulsification and 25 Gauge (25G) Vitrectomy Versus Phacoemulsification Only in Idiopathic Epiretinal Membranes N/A
Completed NCT05171621 - Measuring Subjective Quality of Vision and Metamorphopsia Before and After Epiretinal Membrane and Macular Hole Surgery
Recruiting NCT04306718 - Cultivation of Hyalocytes From ILM and ERM Samples: a Pilot Study N/A
Recruiting NCT01985490 - Change in Foveal Avascular Zone After Removal of Epiretinal Membrane and Internal Limiting Membrane N/A
Completed NCT01238393 - Treatment of Epiretinal Membranes With Ranibizumab N/A
Terminated NCT00333060 - Study of OT-551 Eye Drops to Prevent or Delay Progression of Nuclear Cataracts Following Vitreous Removal Phase 2
Completed NCT05287269 - Ocular Coherence Tomography During Cataract Assessment
Recruiting NCT05138315 - Quantification of Metamorphopsia in Patients With Epiretinal Membranes N/A
Recruiting NCT03661593 - Aniseikonia in Epiretinal Membrane Patients N/A
Completed NCT03457584 - Effect of Air-tamponade on Intraretinal Cystoid Changes After Membrane Peeling N/A