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Enuresis clinical trials

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NCT ID: NCT01786967 Completed - Clinical trials for Urge Urinary Incontinence

Understanding the Response to Fesoterodine Through Genetic Evaluation in the Elderly (URGE)

URGE
Start date: September 2012
Phase: Phase 3
Study type: Interventional

Urge urinary incontinence, characterized by unpredictable and embarrassing large volume urine leakage, is a major health issue for elderly women, as it is incredibly common and significantly impairs quality of life. Although anticholinergic medications are the most common therapy, the investigators are unable to predict an individual's response to a particular drug in terms of both effectiveness and side effects. Through genetic evaluation, the investigators have the potential to personalize and optimize drug therapy for millions of elderly women suffering from urge incontinence.

NCT ID: NCT01784588 Completed - Clinical trials for Stress Urinary Incontinence

Post Market Study Of Single Incision Sling Versus Transobturator Sling for Stress Urinary Incontinence

Solyx
Start date: June 2013
Phase: N/A
Study type: Interventional

The purpose of this research study is to compare the treatment device (Solyx) to a different mesh sling or control device (Obtryx II) for the treatment of symptoms for Stress Urinary Incontinence (SUI). Safety information and patient outcomes will be collected for three (3) years and evaluated.

NCT ID: NCT01784172 Completed - Clinical trials for Urinary Stress Incontinence

Efficacy and Safety Study of Electroacupuncture for Simple Female Stress Urinary incontinence-a Multicenter Trial

Start date: March 2013
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of electroacupuncture (EA) for simple female stress urinary incontinence.

NCT ID: NCT01779323 Completed - Clinical trials for Male Stress Urinary Incontinence

Study of Urethral Mobility in Male Stress Urinary Incontinence Pre- and Post- Placement of Transobturator Sling

Start date: March 2012
Phase:
Study type: Observational

The hypothesis is men with stress urinary incontinence, including those following radical retropubic prostatectomy and other prostate surgery, have preoperative urethral mobility as measured by magnetic resonance imaging (MRI) that improves significantly following sling placement. The investigators theorize that the sling helps with primary hypermobility of this pathophysiologic cause of stress urinary incontinence.

NCT ID: NCT01767519 Completed - Clinical trials for Urinary Incontinence

A Study Evaluating the Efficacy and Safety of BOTOX® or Solifenacin in Patients With Overactive Bladder and Urinary Incontinence

Start date: March 1, 2013
Phase: Phase 3
Study type: Interventional

A study to evaluate the efficacy and safety of BOTOX® or Solifenacin in patients with overactive bladder (OAB) and urinary incontinence.

NCT ID: NCT01766193 Completed - Clinical trials for Urinary Incontinence

Delivery Method and Risk for Urogenital Prolapse 15-20 Years Later

uropro
Start date: August 2012
Phase: N/A
Study type: Observational

The lifetime risk for a woman to undergo surgery for either vaginal prolapse or urinary incontinence is high. Previous studies have shown that pregnancy and childbirth are risk factors for developing prolapse. There is a lack of studies that follow women several years after delivery aiming to find whether symptoms of prolapse are linked to delivery method, ie vacuum, forceps, normal vaginal delivery and cesarean section. The investigators plan this study is to get more knowledge about pathology of prolapse and incontinence, to enable development of preventive strategies for these conditions. Aim of the study is to determine whether the prevalence of symptoms and performed surgery for urogenital prolapse differs among women delivered by vacuum, forceps, normal vaginal delivery and cesarean section 15-20 years after their first delivery. The investigators identify women that delivered their first child at St. Olavs Hospital, Trondheim, Norway between 1990-1997. Questionnaires will be sent to 2500 women (PFIQ-7, PFDI-20, PISQ-12), 600 of whom will get a clinical examination, where pelvic floor musculature is examined by palpation and 4D ultrasound, and a POP-Q quantification of prolapse performed.

NCT ID: NCT01753011 Completed - Clinical trials for Stress Urinary Incontinence

Urethral Length and TOT (Transobturator Tape) Positioning

Start date: May 2007
Phase:
Study type: Observational

This is a prospective, observational, multicenter study of women with surgically-correctable stress urinary incontinence who undergo a TOT-sling operative procedure.

NCT ID: NCT01748110 Withdrawn - Prostate Cancer Clinical Trials

Health Interventions in Men Undergoing Radical Prostatectomy

HIM-UP
Start date: December 2012
Phase: N/A
Study type: Interventional

The goal of the study is to assess the impact of a health intervention, involving both diet and exercise modification, on outcomes following radical prostatectomy for the treatment of clinically localized prostate cancer. The specific urological outcomes expected to be improved are accelerated and/or improved recovery of erectile function (EF), as well as urinary continence, both very commonly affected by this surgery. Furthermore, as demonstrated by changes in responses to various questionnaires, an improvement in overall health-related quality of life is expected. Finally, an improvement in patients participating in the intervention groups in physical parameters, including body mass index (BMI), blood pressure (BP), and metabolic parameters, including serum glucose and cholesterol levels, is expected.

NCT ID: NCT01747343 Completed - Incontinence Clinical Trials

Toilet Training Toddlers and Preschoolers

Start date: November 2012
Phase: N/A
Study type: Interventional

The investigators are interested in determining those procedures that prove to be most efficient and effective in facilitating continence (i.e., "dry pants" or the absence of soiled undergarments), appropriate eliminations (i.e., voids/stools in toilet), and independent requests/initiations to use the toilet. To assess the effectiveness of toilet training methods (procedures), data on toileting skills (in addition to each skill in a given child's curriculum) are collected across the school day (7:30 am-5:45 pm) by the classroom teachers. The primary dependent variables (toileting skills) are continence (i.e., absence of soiled undergarments), appropriate eliminations (i.e., the number of voids/stools made in the toilet), and independent/self requests (i.e., communication by the child with an adult to use the toilet). The toileting procedures are implemented by classroom teachers (undergraduate practicum students) and implementation is monitored by classroom supervisors (graduate teaching assistants). Procedural effectiveness is evaluated on a daily basis by the graduate teaching assistants and on an at-least-weekly basis by faculty supervisors.

NCT ID: NCT01724242 Withdrawn - Breast Cancer Clinical Trials

Vaginal DHEA for Women After Breast Cancer

Start date: February 2013
Phase: Phase 2/Phase 3
Study type: Interventional

There does not appear to be a consensus regarding the treatment of vaginal dryness in women who have a contraindication to the use of estrogen products. DHEA, when used locally, may improve the symptoms of vaginal dryness due to its chemical properties.