Clinical Trials Logo
  1. Home
  2. Endothelial Function
  3. NCT01713374

Physiological Assessment of the Endothelium - Circadian Rhythm and Role of the Sympathetic Nervous System — PAN  

Endothelial Function Clinical Trial

Official title:
Studies on the Physiological Meaning of Flow-mediated Constriction, Flow-mediated Dilatation and Vasomotion/Flowmotion: Circadian Variability and Role of the Sympathetic Nervous System.

Clinical Trial Summary

The purpose of this study is to determine whether interventions aimed at increasing sympathetic tone modify endothelial function measures as assessed by the measurement of flow-mediated dilation (FMD) and constriction (FMC). The investigators hypothesize that the three interventions under study will increase FMC while causing a blunting in FMD.

Further, the investigators plan to study the circadian variability of FMC and FMD. The investigators hypothesize a peak of FMD in the late hours of the day and a peak of FMC in the early hours.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Basic Science

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01713374
Study type Interventional
Source Johannes Gutenberg University Mainz
Contact
Status Completed
Phase N/A
Start date October 2012
Completion date March 2014
View Details
See also
  Status Clinical Trial Phase
Completed NCT03301402 - Air Purifier to Improve Endothelial Function and Carotid Intima Thickness N/A
Recruiting NCT02500329 - Effect of Gemigliptin or Acarbose on Endothelial Function in Type 2 DM Patients Phase 4
Completed NCT01947790 - Pioglitazone Regress Left Ventricular Mass in Type 2 Diabetes With Ischeamia Heart Disease Phase 4
Completed NCT01028599 - Effect of Physical Training on Oxygen Uptake and Endothelial Function in Heart Transplant Recipients N/A
Completed NCT00575120 - Endothelial Function Assessed With BOLD-MRI N/A
Active, not recruiting NCT05451641 - Blood Flow Restriction Resistance Training Intervention on Vascular Function N/A
Completed NCT03651713 - Hyperglycemia, Exercise, and Endothelial Function N/A
Completed NCT00844714 - Cardiovascular Risk Markers in Patients With Rheumatoid Arthritis: Effect of Rituximab Therapy N/A
Completed NCT01256957 - Effect of HEPA Air Filters on Subclinical Markers of Cardiovascular Health N/A
Completed NCT00967252 - Impact of Chronic Statin Use During Surgery on Inflammation and Infection Rates N/A
Completed NCT00728221 - Evaluation and Standardization of Ginseng and it's Components for Blood Pressure Regulation Phase 2
Completed NCT00845013 - Epidemiology and Pathogenesis of HIV-Associated Pulmonary Hypertension
Completed NCT00534651 - Paracetamol and Endothelial Function in Patients With Stable Coronary Artery Disease Phase 4
Recruiting NCT04689477 - Non-invasive Characterization of Systemic Microvascular Reactivity by Near-infrared Diffuse Optical Spectroscopy in COVID-19 Patients
Completed NCT01829542 - Dose-dependent Effects of Blueberry Polyphenols on Endothelial Function in Healthy Individuals N/A
Completed NCT01610401 - The Metformin-FMD Trial Phase 4
Terminated NCT00942643 - Endothelial Damage and Atherosclerosis in Obstructive Sleep Apnea N/A
Completed NCT05235958 - VascuFit: Exercise and Vascular Aging N/A
Not yet recruiting NCT06288828 - The Efficacy of Aerobic Exercise Training on Autonomic Nervous System and Endothelial Function in Patients With Compensated Cirrhosis N/A
Completed NCT05396079 - Effect of Tahini in Oxidative Stress and Endothelial Function in Diabetes N/A