Fentanyl Clinical Trial
Official title:
Effect of Topically Administered Levobupivacaine- Fentanyl Versus Levobupivacaine- Dexamethasone Combination in the Control of Pain After Endoscopic Sinus Surgery: A Randomized Controlled Trial
Chronic sinusitis (CRS) is a high incidence disease characterized by pus, nasal obstruction, olfactory disturbance, headache, and other symptoms, lasting for more than 12 weeks, with severe cases having ocular compression and visual impairment, which can cause cranial, eye, and lung complications. Chronic sinusitis is a high-risk disease.
One of the main concerns about using packing is that the removal is usually very painful and can be very bothersome. This procedure may even result in syncope by the activation of the vasovagal reflex system. There have been a few studies suggesting that nasal packs should not be used because removal from the nose causes serious discomfort and is painful. Many patients who have undergone nasal surgery report that the removal of the pack was the most painful part of the experience. Postoperative pain is an acute inflammatory pain that starts with surgical trauma and ends with tissue healing. It can be harmful to organ systems by initiating inflamma¬tion through different mechanisms, and the alleviation of postoperative pain is considered important for obtaining homeostasis. Pain may initiate atelectasis due to improper coughing, immobilization may cause thromboembolism and catecholamine discharge may induce cardiovascular side effects and undesired changes in neuroendocrine or meta¬bolic function ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02840006 -
Spinal Anesthesia Associated With General Anesthesia in Coronary Artery Bypass
|
Phase 4 | |
| Recruiting |
NCT06210061 -
Propofol-Fentanyl-Dexmedetomidine and Propofol-Fentanyl-Sevoflurane Anesthesia for Major Spine Surgery Under Somato Sensory- and Motor- Evoked Potential Monitoring
|
N/A | |
| Completed |
NCT06052111 -
Dexmedetomidine vs Fentanyl on Time to Extubation in Patients Undergoing Laparoscopic Sleeve Gastrectomy
|
N/A | |
| Recruiting |
NCT05243940 -
Opioid-free Anesthesia in Thyroidectomies
|
N/A | |
| Recruiting |
NCT03869346 -
Impact of CYP3A4*1G Polymorphism on Non-analgesic Effects of Fentanyl in Chinese Han Patients
|
||
| Completed |
NCT03607110 -
Comparison of Efficacy of Anesthesia Administered by Endoscopist or Anesthesiologist on Colonoscopy
|
||
| Recruiting |
NCT06386783 -
Fentanyl Versus Dexmedetomidine as an Adjuvant to Bupivacaine in Spinal Anesthesia ; Peritoneal Symptomatic Effects
|
Phase 3 | |
| Completed |
NCT04397406 -
Dexmedetomidine or Fentanyl as Additives to Epidural Levobupivacaine in Painless Labor
|
Phase 4 | |
| Not yet recruiting |
NCT05985850 -
Evaluating Tetrahydrocannabinol as an Adjunct to Opioid Agonist Therapy
|
Phase 2 | |
| Withdrawn |
NCT02985177 -
A RCT of a Combination of Analgesics for Pain Management in Children With a Suspected Fracture
|
Phase 4 | |
| Completed |
NCT03901716 -
Comparison of Sufentanil, Fentanyl and Remifentanil in Combination With Midazolam During Bronchoscopy Under Conscious Sedation
|
Phase 4 | |
| Recruiting |
NCT06051227 -
Fentanyl OR Esketamine for Traumatic PAIN (FORE-PAIN) Trial
|
Phase 3 | |
| Completed |
NCT04597320 -
Esketamine Sedation and Fentanyl Sedation in Pediatric Dental Patients
|
Phase 4 | |
| Active, not recruiting |
NCT03198208 -
Intraoperative Fentanyl Dose on Respiratory Complications
|
N/A | |
| Recruiting |
NCT05805241 -
Pharmacogenetics Analysis of Fentanyl Administered in Newborns
|
||
| Completed |
NCT02031016 -
Remifentanil vs Fentanyl During Cardiac Surgery and Chronic Thoracic Pain
|
Phase 4 | |
| Withdrawn |
NCT01488149 -
Intrapartum Epidural Fentanyl and Breast-feeding in the Immediate Postpartum Period: a Prospective Cohort Study
|
||
| Terminated |
NCT03948464 -
Slow-Release Oral Morphine for the Treatment of Opioid Use Disorder
|
Phase 3 | |
| Completed |
NCT04971759 -
Dexmedetomidine to Levobupivacaine for Transversus Abdominis Plane Block in Elderly Patients Undergoing Inguinal Hernia Repair Surgery
|
Phase 2/Phase 3 | |
| Recruiting |
NCT05367336 -
Platelet Reactivity With Fentanyl, Morphine, or no Narcotic
|
Early Phase 1 |