Degarelix in the Treatment of Endometriosis Recurrence

Status Completed

Clinical Trial Summary

The long acting GnRH antagonist degarelix will be tested for the treatment of women with endometriosis recurrence compared with classical GnRH analog treatment. Pain symptom disappearance and disease free time during follow-up will be the outcomes for establishing which medical treatment is the best in endometriosis recurrence treatment.

Clinical Trial Description

Endometriosis is a chronic disease affecting 5-10% of women in reproductive age, showing recurrence after surgery at least in 20-50% after 5 years of follow-up. The long acting GnRH antagonist degarelix, which do not have the flare-up effect at the opposite of GnRH agonist and strongly suppress LH secretion and thecal cell activity may show a better effects on endometrial implants than GnRH agonist. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01712763
Study type	Interventional
Source	Centre for Endocrinology and Reproductive Medicine, Italy
Contact
Status	Completed
Phase	Phase 3
Start date	November 2012
Completion date	March 2016

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