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Emergencies clinical trials

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NCT ID: NCT03827421 Terminated - Brain Damage Clinical Trials

Junior Emergency Physician Learning Curve to Perform Transcranial Doppler on Brain-damage Patients

Transcranius
Start date: December 18, 2018
Phase:
Study type: Observational [Patient Registry]

Transcranial Doppler is a noninvasive tool. Using velocity measurements and pulsatility index it allows the evaluation of cerebral haemodynamics. In patients presenting brain injury cerebral perfusion may be impaired. Indirect cerebral blood flow can be monitored and risk of neurological worsening can be detected using transcranial Doppler. Education and performance of emergency physicians must be evaluated on brain-injured patients because this tool is operator dependent. The main objective of this study is to estimate the average number of exams required to learn transcranial Doppler within junior emergency physicians with the achievement of their learning curve. We will perform a prospective, monocentric, observational study within the neurosurgical resuscitation department of Grenoble Alpes University Hospital.

NCT ID: NCT03821584 Terminated - Emergencies Clinical Trials

Brain Perfusion Assessment in the Acute Phase of Migraine Aura

PERCAM
Start date: March 1, 2019
Phase:
Study type: Observational

The aim of the study is to determine the proportion of patients with change in brain perfusion during the acute phase of migraine attack with aura.

NCT ID: NCT03756038 Terminated - Acute Pain Clinical Trials

Benzodiazepines for the Reduction of Distress and Pain During and After Emergency Department Care

Start date: January 25, 2019
Phase: Phase 2
Study type: Interventional

In this proposal, the investigators will determine if a single dose of oral lorazepam reduces distress, pain severity, and need for opiate analgesics both in the ED and in the acute recovery period after discharge. The investigators will compare the lorazepam arm to a placebo arm.

NCT ID: NCT03569917 Terminated - Clinical trials for Patients Receiving Ceftriaxone in Hospital Emergency Unit

Identification of Gut Microbiome Biomarkers Associated to Acquisition of Enterobacteriae Highly Resistant to Third Generation Cephalosporines Following Ceftriaxone Treatment.

ARCMI
Start date: December 19, 2018
Phase: N/A
Study type: Interventional

Patients receiving Ceftriaxone 1 gram or 2 grams per day during their presence in emergency unit of hospital whatever their medical condition, will be included. Rectal swabs will be collected at inclusion and at days 5 and 30 to perform analysis. Analysis will be performed to characterize gut microbiome in order to detect intestinal microbiome profiles significantly associated with protection against colonization by third generation cephalosporin resistant Enterobacteriae.

NCT ID: NCT03562702 Terminated - Dehydration Clinical Trials

Comparing Speedlyte and IV Rehydration Treating Children With Gastroenteritis in a Pediatric Emergency Department (ED)

Start date: July 1, 2018
Phase: N/A
Study type: Interventional

To compare length of stay (LOS) of pediatric patients in a pediatric emergency room presenting with Gastroenteritis treated with IV rehydration versus oral Speedlyte rehydration.

NCT ID: NCT03472872 Terminated - Headache Clinical Trials

A Comparative Efficacy Trial of IV Acetaminophen Versus IV Ketorolac for Emergency Department Treatment of Generalized Headache

Start date: September 5, 2017
Phase: Phase 4
Study type: Interventional

This randomized, double-blind trial will compare the clinical efficacy of IV acetaminophen to that of IV ketorolac as adjuncts to standard therapy (prochlorperazine and diphenhydramine) in the treatment of patients presenting to the emergency department with chief complaint of "headache" or variants thereof.

NCT ID: NCT03432208 Terminated - Abdominal Pain Clinical Trials

A Pilot Study to Assess the Value of EUS vs EGD in Emergency Room Patients Referred for EGD

Start date: May 27, 2016
Phase: N/A
Study type: Interventional

Emergency room patients referred for esophago-gastro-duodenoscopy (EGD) often have many possible causes for their symptoms. These inevitably undergo further testing if EGD is inconclusive, which adds costs and inevitably prolongs emergency room length of stay (LOS).EUS has traditionally been used after EGD for a myriad of costs reasons that no longer apply. We therefore propose a prospective pilot study to determine whether PEUS can reduce LOS and resource utilisation in emergency room patients referred for EGD.

NCT ID: NCT03246620 Terminated - Acute Agitation Clinical Trials

Oral Olanzapine Versus Haloperidol or Diazepam

Start date: September 1, 2017
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether oral olanzapine is safer (fewer adverse events) and more effective (shorter time to sedation) than conventional haloperidol or diazepam when used in the management of acute agitation in the emergency.

NCT ID: NCT03214809 Terminated - Dyspnea Clinical Trials

The Use of a Point-of-care Thoracic Ultrasound Protocol for Hospital Medical Emergency Teams

METUS
Start date: January 18, 2019
Phase: N/A
Study type: Interventional

Study to assess the possible effects of the use of a point-of-care thoracic ultrasound protocol for hospital medical emergency teams (MET)

NCT ID: NCT03182465 Terminated - Clinical trials for Febrile Neutropenia, Drug-Induced

Predictive Value of ProCalcitonin for the Detection of Bacteraemia in Patients Presenting to the Emergency Department for Low Risk Chemo-induced Febrile Neutropenia

CALIF
Start date: October 4, 2017
Phase: N/A
Study type: Interventional

CALIF study is a monocentric observational study which aim is to analyse the value of adding procalcitonin (PCT, a pre-hormon increased in bacterial infection and septicaemia) in the management of chemo-induced febrile neutropenia occurring in patient with solid tumour. Febrile neutropenia will be managed according to international guidelines. PCT will be dosed at initial presentation. Primary objective is to determine the optimal value of PCT for the detection of septicaemia in low risk (according to MASCC score). The investigators plan also to compare two risk stratification scores: the validated MASCC score and a recently developed score which includes PCT and other more objective items.