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Clinical Trial Summary

This is a randomized controlled trial comparing the outcomes of treatment and non-treatment of elevated blood pressures in early pregnancy.


Clinical Trial Description

Patients will be randomized to treatment of elevated blood pressures (120 or greater systolic OR 80 or greater diastolic) versus non-treatment. After randomization to treatment, patient's will be treated with either nifedipine or labetalol (both medications that are standard of care for treatment of elevated blood pressure during pregnancy). The purpose of this study is two-fold: 1) Determine if treatment of elevated blood pressures (120 or greater systolic OR 80 or greater diastolic) versus non-treatment improves maternal and fetal outcomes and 2) determine if ICG directed treatment is optimal as ICG will not be used to determine treatment medication (this will be done by secondary analysis after conclusion of the study). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05955040
Study type Interventional
Source Marshall University
Contact Jesse Cottrell, MD
Phone 304-691-1400
Email cottrellje@marshall.edu
Status Recruiting
Phase Phase 2
Start date July 11, 2023
Completion date December 31, 2024

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