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Elderly Patients clinical trials

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NCT ID: NCT04180800 Completed - Social Isolation Clinical Trials

Studying the Association Between Folic Acid Deficiency and Social Isolation for Elderly Patients

Start date: January 23, 2020
Phase:
Study type: Observational

Social isolation among elderly people is a frequent and major determinant for health. The risk of premature death is 2 to 5 time higher for socially isolated people, similarly for morbidity, duration of healing and complications rate. Denutrition is also frequent for elderly people with potentially serious consequences. Vitamin deficiency, especially in B9 and B12 vitamins, are often associated with denutrition among elderly people. Folic acid (vitamin B9) is not influenced by inflammation and folic acid income are necessarily exogene. Vitamin B9 is provided by fresh fruits and vegetables, and giblets. The investigators observed a high prevalence in folic acid deficiency for socially isolated elderly patients. The investigators made the hypothesis that a folic acid defiency is associated with social isolation for elderly people. The primary purpose is the study of the association between folic acid deficiency (measured by dosing of plasma concentration of vitamin B9) and social isolation evaluated by Lubben Social Network Scale in 6 questions. The secondary purposes are the study of the correlation between folic acid deficiency and social conditions, nutritional status, biological data, poly pharmacy, cognitive functions, dependency and length of stay at hospital.

NCT ID: NCT04065763 Completed - Elderly Patients Clinical Trials

Correlation of the Dural Sac Dimension With the Spread of Spinal Anesthesia

Start date: October 10, 2019
Phase:
Study type: Observational

Cerebrospinal fluid volume is an important factor that influences peak block height and regression of sensory and motor blockade. The aim of this study is to evaluate the effect of dural sac dimension on the spread of spinal anesthesia in elderly patient using ultrasound.

NCT ID: NCT03868007 Completed - Clinical trials for Acute Coronary Syndrome

Protective Effects of RIC in Elderly With Acute Ischemic Stroke Complicating Acute Coronary Syndrome

RIC-ACS
Start date: March 10, 2019
Phase: N/A
Study type: Interventional

Remote ischemic conditioning (RIC) is a noninvasive strategy in which one or more cycles of brief and transient limb ischemia confers protection against prolonged and severe ischemia in distant organs.This study aimed to investigate whether RIC is safe and effective in patients with AIS complicating ACS

NCT ID: NCT03858465 Completed - Hip Fractures Clinical Trials

Comparison of Phenylephrine and Ephedrine in the Treatment of Hemodynamic Disorders After Spinal Anesthesia in the Elderly

HypoGer
Start date: February 1, 2019
Phase: N/A
Study type: Interventional

Spinal anesthesia is often used for lower limb surgery in elderly. Hypotension is a side effect of spinal block. In this study, intravenous ephedrine and phenylephrine will be compared with each other to prevent spinal anesthesia-induced hypotension, which is defined in absolute terms as a systolic blood pressure < 100 mmHg or in relative terms as a 20% fall of systolic blood pressure from baseline.

NCT ID: NCT03828227 Active, not recruiting - Quality of Life Clinical Trials

QoL in mCRC Elderly Patients Receiving First-line Therapy Based on Simplified Geriatric Parameters.

COLAGE
Start date: June 14, 2019
Phase: Phase 3
Study type: Interventional

A national, multicenter, open-label, randomized phase III study. The trial aim is to determine the best therapeutic strategies according with the HRQoL.

NCT ID: NCT03800771 Completed - Elderly Patients Clinical Trials

DOuble tasK Test On ergometeR - Basic Research on Acceptability and Use

DOKTORBRAU
Start date: August 28, 2019
Phase: N/A
Study type: Interventional

The goal of the study is to show the concordance between the dual-task test achieved usually on an electronic treadmill and the dual-task test achieved with a cyclo-ergometer.

NCT ID: NCT03797196 Active, not recruiting - Immunosuppression Clinical Trials

RCT Comparing Immunosuppressive Regimens in Elderly Renal Transplant Recipients

OPTIMIZE
Start date: July 29, 2019
Phase: Phase 4
Study type: Interventional

Open label, randomized, multicenter, intervention trial comparing standard immunosuppression with tacrolimus and mycophenolate mofetil with a low exposure tacrolimus regimen in combination with everolimus. The primary objective is to test the hypothesis that an age-adapted immunosuppressive regimen targeted at reduced immunosuppression with low calcineurin inhibitor (tacrolimus) exposure in combination with everolimus will result in improved outcome in elderly recipients of A: Kidneys from older deceased donors (>64 years) and B: Kidneys from living donors (all ages) and younger deceased donors (<65 years).

NCT ID: NCT03743961 Terminated - Elderly Patients Clinical Trials

Geriatric Intervention Contribution on Quality of Life of Elderly Patients With Metastatic Neoplasia

QUALI
Start date: November 21, 2018
Phase:
Study type: Observational

The aim of this study is to describe the impact of : Geriatric intervention contribution on quality of life of elderly patients receiving systemic treatments for metastatic neoplasia

NCT ID: NCT03335826 Completed - Elderly Patients Clinical Trials

Epidural Anesthesia and Long-term Outcomes in Elderly Patients After Surgery

Start date: August 1, 2017
Phase: N/A
Study type: Interventional

Surgical resection is one of the most important treatments for solid organ cancer. Whereas cancer recurrence and/or metastasis are the major reasons of treatment failure. The outcomes after surgery are mainly dependent on the balance between the immune function of the body and the invasiveness of residual cancer. Preclinical and retrospective studies suggest that anaesthetic techniques and drugs may affect the long-term outcomes in patients undergoing cancer surgery. The investigators hypothesize that epidural anesthesia-analgesia may improve long-term survival in the elderly who undergo major surgery for cancer.

NCT ID: NCT03324711 Terminated - Alzheimer Disease Clinical Trials

Psychometric Validation of the "Antillanisée" Version of the Mini Mental State Examination (MMSEa)

MMENSEA
Start date: November 15, 2016
Phase: N/A
Study type: Interventional

The main objective of the study is to analyze the psychometric properties of the "antillanisée" version of the Mini Mental State Examination (MMSEa). The methodology used will permit to explore the feasibility, acceptability, validity and reliability of the tool. The psychometric validation of a version adapted transculturally will increase the value of the results obtained with this test and will make it possible to refine the screening of existing cognitive disorders for elderly subjects with Alzheiner's disease or related disorders.