Clinical Trials Logo
  1. Home
  2. Effects of Chemotherapy
  3. NCT02306837

Consolidation Chemotherapy After Autologous Stem Cell Transplantation for Lymphoid Malignancies

Effects of Chemotherapy Clinical Trial

Official title:
A Phase II Trial of Consolidation Chemothetapy for Patients With Relapse or Refractory Lymphoid Malignancies After Autologous Stem Cell Transplantation

Clinical Trial Summary

To imporve the outcome of patients with relapsed/refractory lymphoma, we conduct a clinical trial to test the efficacy and feasibility of consolidation chemotherapy after autologous stem cell transplantation

Clinical Trial Description

Patients with relapsed or refractory lymphoma will be included. All patients will undergo PBSC mobilization with CTX and G-CSF. After sucessful collection of CD34+ over 1x109/L, autologous stem cel ltransplantation with Bu-Cy-E conditioning will be given. Two months after auto-HSCT, a PET-CT will be performed and all patients with CR, CRu and PR will recieved 3 cycles of mini-Bu-Cy-E as consolidation 3, 6 and 9 months after auto-HSCT. For patients with SD or PD after auto-HSCT will refered to the allogeneic transplantatio program and take off the study. ;

Study Design

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02306837
Study type Interventional
Source Shanghai Jiao Tong University School of Medicine
Contact Jiong Hu, M.D,
Phone 86-21-64370045
Email hujiong@medmail.com.cn
Status Recruiting
Phase Phase 2
Start date September 2014
Completion date September 2019
View Details
See also
  Status Clinical Trial Phase
Not yet recruiting NCT05529940 - NeoFOL-R Trial (Perioperative Versus Adjuvnat FOLFIRINOX in Resectable Pancreatic Cancer) Phase 3
Completed NCT02771470 - Intestinal Microflora in Lung Cancer After Chemotherapy Phase 1
Completed NCT02454673 - Therapeutic Individualization for Patients With Locally Advanced Gastric and Gastroesophageal Cancer N/A
Completed NCT02454647 - Induction Chemotherapy, Chemoradiotherapy and Surgery in Locally Advanced Gastric Cancer Patients N/A
Completed NCT01432223 - Primary Chemotherapy With Anthracycline Followed by Nab-paclitaxel and Trastuzumab Phase 2
Completed NCT02767388 - Electrophysiological Biomarkers of Chemotherapy-related Cognitive Impairment and Recovery
Recruiting NCT02555592 - Strategy of Surgical Resection With Adjuvant Therapy for IIIA NSCLC and N2 Disease Only in Subaortic or Paraaortic Level N/A
Suspended NCT02121405 - Randomized Trial of Primary Surgery Followed Selective Radiochemotherapy for Rectal Cancer With MRI Negative CRM Phase 3
Recruiting NCT02226380 - FOLFOX6 as Neoadjuvant Chemotherapy in Local Advanced Gastric Cancer Phase 2
Completed NCT00911352 - Cryotherapy Intervention for Docetaxel-induced Nail Toxicities Phase 2/Phase 3
Completed NCT03840824 - Blood Spot Self-administered Test and Assay
Active, not recruiting NCT01490060 - Fosaprepitant in Patients Receiving Ifosfamide-based Regimen N/A
Completed NCT02395341 - The Longitudinal Ovarian Reserve Study N/A
Recruiting NCT05268991 - Aging and Frailty Study
Recruiting NCT03885388 - Combination of Methotrexate(MTX) and Actinomycin(ACTD) in the Low Risk Gestational Trophoblastic Neoplasma （GTN） Patients With Score of 5-6 Phase 2/Phase 3
Completed NCT02375776 - Improving Outcomes in Cancer Patients on Oral Anti-Cancer Medications Using a Multi-modal Mobile Health Intervention N/A
Enrolling by invitation NCT02074241 - Molecular Markers of Chemosensitivity for Bladder Cancer N/A
Completed NCT01143844 - Assessing Fertility Potential in Female Cancer Survivors
Recruiting NCT02169388 - Intestinal Microflora in Colorectal Cancer (CRC) After Chemotherapy Phase 1
Completed NCT03402295 - Superiority of VCD Versus CTD in Patients With Newly Diagnose Multiple Myeloma Eligible for Transplantation Phase 3