Intestinal Microflora in Colorectal Cancer (CRC) After Chemotherapy

Status Recruiting

Clinical Trial Summary

Probiotics modulate the gut microflora and immune status in CRC,which can reduce the side effects of chemotherapy such as diarrhea,infection,neutropenia etc.

Clinical Trial Description

Chemotherapy destroys the intestinal mucosal barrier, affects intestinal flora, causing bacterial translocation, infection and other complications; Probiotics may restore the intestinal immunity, mucosal barrier, and nutrient absorption.The adverse effects of chemotherapy and the malnutrition status may be relieved via probiotic administration. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Supportive Care

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02169388
Study type	Interventional
Source	Shandong University
Contact	Yanqing Li, MD.PhD.
Phone	86-531-82169236
Email	liyanqing@sdu.edu.cn
Status	Recruiting
Phase	Phase 1
Start date	June 2014
Completion date	January 2015

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