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Edema clinical trials

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NCT ID: NCT04505306 Completed - Clinical trials for Diabetic Macular Edema

Short-pulse Subthreshold vs Infrared Micropulse for Diabetic Macular Edema

Start date: January 1, 2015
Phase: N/A
Study type: Interventional

When applied according to manufacturer recommendations, short-pulse system may yield more temporary reduction in edema while infrared micropulse system may yield slightly better functional outcomes.

NCT ID: NCT04501367 Recruiting - Vitrectomy Clinical Trials

Assessing the Efficacy and Safety fo DEXTENZA, Sustained Release Dexamethasone 0.4 mg Insert(s) for the Treatment of Pain, Inflammation, and Cystoid Macular Edema Following 27 Gauge Vitrectomy With Internal Limiting Membrane Peel for the Treatment of Retinal Edema Associated With Macular Pucker.

Start date: April 27, 2021
Phase: Phase 4
Study type: Interventional

Assessing the efficacy and safety of DEXTENZA, sustained release dexamethasone 0.4 mg inserts following 27 gauge vitrectomy with internal limiting membrane peel

NCT ID: NCT04499703 Completed - Clinical trials for Macular Degeneration

Evaluation of the Retinal Health Monitoring System Thickness Module

Start date: November 11, 2020
Phase:
Study type: Observational

Evaluate the ability and accuracy of the Retinal Health Monitoring System - Retinal Thickness Module (RHMS - RTM).

NCT ID: NCT04498169 Completed - Corneal Edema Clinical Trials

A Phase 2 Study Evaluating the Safety and Efficacy of Netarsudil Ophthalmic Solution in Patients With Corneal Edema Due to Fuchs Corneal Dystrophy

Fuchs
Start date: September 17, 2020
Phase: Phase 2
Study type: Interventional

Two different dosing regimens (QD and BID) of netarsudil will be studied to evaluate their efficacy in reducing or resolving corneal edema in subjects with FCD.

NCT ID: NCT04483843 Completed - Clinical trials for Pulmonary Edema Cardiac Cause

Cosmic Weather and Cardiogenic Pulmonary Edema

Start date: March 1, 2019
Phase:
Study type: Observational

Retrospective clinical study to evaluate whether there is any correlation between the pre-hospital incidence of cardiogenic pulmonary oedema (CPE) in the selected region and the space weather parameters.

NCT ID: NCT04469595 Active, not recruiting - Clinical trials for Diabetic Macular Edema

A Study of Intravitreal ILUVIEN® Implant as Baseline Therapy in Patients With Early Diabetic Macular Edema (DME)

NEW DAY
Start date: August 31, 2020
Phase: Phase 4
Study type: Interventional

This is a randomized, masked, active-controlled, parallel-group, multi-center study that will assess the efficacy of ILUVIEN as a baseline therapy in the treatment of Center Involving DME (CI-DME). The study will enroll patients who are either treatment naïve or have not received any DME treatments for the preceding 12 months as documented in medical records. Patients who received DME treatment >12 months before screening, must not have received >4 intravitreal injections. The study will compare 2 treatment regimens: ILUVIEN intravitreal implant (0.19 mg) followed by supplemental aflibercept as needed per protocol criteria (2 mg/0.05 mL), compared to intravitreal aflibercept loading dose (2 mg administered by intravitreal injection every 4 weeks for 5 consecutive doses) followed by supplemental aflibercept as needed per protocol criteria (2 mg/0.05 mL).

NCT ID: NCT04468152 Completed - Clinical trials for Diabetes Mellitus, Type 2

Advanced Glycation End Products Are Associated With Diabetic Macular Edema

Start date: July 7, 2018
Phase: N/A
Study type: Interventional

Diabetic macular edema can develop at all stages of diabetic retinopathy, causing visual impairment and blindness. Modern diets are high in advanced glycation end products (dAGEs), derived from processing methods, exerting a pivotal role in promoting diabetic retinopathy risk. In this cross-sectional study, we investigate the relationship between dietary and serum levels of AGEs and DME in type 2 diabetic subjects.

NCT ID: NCT04464694 Not yet recruiting - Clinical trials for Diabetic Macular Edema

Pre-vitrectomy Intravitreal Ranibizumab for Patients With Proliferative Diabetic Retinopathy Combined With Diabetic Macular Edema

Start date: September 1, 2020
Phase: Phase 4
Study type: Interventional

To investigate ranibizumab's benefit on prevention of early postoperative vitreous haemorrhage in PDR-DME patients receiving vitrectomy.

NCT ID: NCT04463303 Not yet recruiting - Clinical trials for Detecting the Number of B-lines in Lung Ultrasound and Its Accuracy in Diagnosis of Weaning Induced Pulmonary Oedema

The Role of Lung Ultrasound in The Diagnosis of Weaning -Induced Pulmonary Edema

Start date: July 2020
Phase:
Study type: Observational

The aim of the work is to 1. Assess the incidence of weaning induced pulmonary adema(WIPO). 2. Assess the risk factors of WIPO. 3. Evaluate the role of lung ultrasound in detecting WIPO during spontenous breathing trial(SBT). 4. Detect the threshold of B-line increase (Delta-B-lines) that provided the best diagnostic accuracy of WIPO.

NCT ID: NCT04455399 Completed - Clinical trials for Diabetic Macular Edema

Time Efficiency Comparison of Two IntraVitreal Injection Techniques

TIVI
Start date: November 9, 2020
Phase: N/A
Study type: Interventional

Prospective, single-center, randomized, clinical trial (RCT) comparing the time efficiency and safety of a single-use intravitreal injection (IVI) guide versus a traditional technique using a dual blade speculum among patients undergoing IVI for various indications.