Clinical Trials Logo

Eczema clinical trials

View clinical trials related to Eczema.

Filter by:

NCT ID: NCT03562377 Completed - Atopic Dermatitis Clinical Trials

Vaccine Responses in Tralokinumab-Treated Atopic Dermatitis - ECZTRA 5 (ECZema TRAlokinumab Trial No. 5)

ECZTRA 5
Start date: July 13, 2018
Phase: Phase 2
Study type: Interventional

The purpose of this trial is to test if treatment with the trial drug, tralokinumab, can affect the body's immune response to vaccines. The trial will also evaluate the efficacy of tralokinumab when it is given concomitantly with vaccines.> The trial includes a screening period of 2 to 6 weeks, a treatment period of 16 weeks (Weeks 0 to 16), and a 14-week off-treatment follow-up period for the assessment of safety (Weeks 16 to 30). Eligible subjects may transfer to an open-label, long-term trial at Week 16 or later.

NCT ID: NCT03559270 Terminated - Atopic Dermatitis Clinical Trials

A Study of Baricitinib (LY3009104) in Participants With Moderate to Severe Atopic Dermatitis

BREEZE-AD6
Start date: June 27, 2018
Phase: Phase 3
Study type: Interventional

This open-label study will evaluate the long-term efficacy and safety of baricitinib in adult participants with moderate to severe atopic dermatitis (AD).

NCT ID: NCT03559075 Completed - Atopic Dermatitis Clinical Trials

Clinical vs. Anecdotal Evidence - Pediatric Atopic Dermatitis

Start date: July 2, 2018
Phase:
Study type: Observational

In dermatology, topical anti-inflammatory medications, such as corticosteroids, are the mainstay treatment of managing patients with atopic dermatitis. However, caregivers are often apprehensive about choosing a topical steroid for a variety of reasons. Many caregivers are not aware that clinical trial evidence for these medications exist, and instead may rely on anecdotal evidence in choosing to take these medications. Because fear of the drug is inherently subjective, it can be modified with appropriate reassurance and presentation of evidence. The goal of the study is to learn whether caregivers are more confident in treating a child's atopic dermatitis after being presented with varying amounts of information.

NCT ID: NCT03556592 Completed - Atopic Dermatitis Clinical Trials

Drug-drug Interaction Trial With Tralokinumab in Moderate to Severe Atopic Dermatitis - ECZTRA 4

Start date: August 13, 2018
Phase: Phase 1
Study type: Interventional

The purpose of this trial is to investigate if tralokinumab changes the metabolism of selected CYP substrates in adults with moderate-to-severe AD after: - 14 weeks of treatment with tralokinumab - a single dose of tralokinumab

NCT ID: NCT03553615 Withdrawn - Atopic Dermatitis Clinical Trials

Open-label Pilot Clinical Trial of Oral Ivermectin to Treat Atopic Dermatitis

Start date: December 2018
Phase: Phase 2
Study type: Interventional

This pilot trial studies how well a novel oral therapeutic agent performs to treat patients with atopic dermatitis, particularly facial dermatitis.

NCT ID: NCT03549416 Recruiting - Atopic Dermatitis Clinical Trials

BioDay Registry: Data Collection Regarding the Use of New Systemic Treatment Options in Patients With Atopic Dermatitis

BioDay
Start date: January 1, 2018
Phase:
Study type: Observational [Patient Registry]

The BioDay Registry aims to address the need for daily practice data regarding the effectiveness and safety of new systemic treatment options (like biologics and Janus kinase inhibitors) in patients with atopic dermatitis and effect on other atopic comorbidities in a multicenter setting. The registry already consists of several additional modules concerning atopic comorbidities, like food allergy and asthma, and a module for conjunctivitis during biologic treatment.

NCT ID: NCT03542994 Completed - Psoriasis Clinical Trials

A Study of EDP1066 in Healthy Participants and Participants With Mild to Moderate Psoriasis and Atopic Dermatitis

Start date: April 24, 2019
Phase: Phase 1
Study type: Interventional

Evelo will investigate the safety and tolerability of EDP1066 and its potential to be a medicinal product in healthy volunteers and individuals with mild to moderate psoriasis and atopic dermatitis.

NCT ID: NCT03540043 Completed - Clinical trials for Atopic Dermatitis Eczema

Thykamine Safety and Efficacy Study in Mild-to-Moderate Atopic Dermatitis

Start date: October 23, 2017
Phase: Phase 2
Study type: Interventional

A Phase 2, multicenter, double-blind, placebo control study evaluating the safety and efficacy of Thykamine in adult patient suffering of mild-to-moderate Atopic Dermatitis

NCT ID: NCT03539601 Terminated - Atopic Dermatitis Clinical Trials

A Study of Crisaborole Ointment 2%; Crisaborole Vehicle; TCS and TCI in Subjects Aged ≥ 2 Years, With Mild-moderate AD

Start date: April 27, 2018
Phase: Phase 4
Study type: Interventional

This 4-week study will evaluate the safety and efficacy of crisaborole ointment 2%; crisaborole vehicle; topical corticosteroid and topical calcineurin inhibitor, applied twice daily (BID) in subjects who are at least 2 years of age with mild-moderate AD. A Sub-Study of Optical Coherence Tomography and Biomarkers in Subjects ages 2 to <18 years old, with Mild to Moderate Atopic Dermatitis, treated with Crisaborole Ointment, 2% or Crisaborole Vehicle Ointment or Hydrocortisone Butyrate 0.1% Cream applied BID will also be conducted at select sites.

NCT ID: NCT03533751 Completed - Atopic Dermatitis Clinical Trials

Efficacy, Safety, and Pharmacokinetic Profile of Etokimab (ANB020) in Adult Participants With Moderate-to-Severe Atopic Dermatitis

ATLAS
Start date: June 19, 2018
Phase: Phase 2
Study type: Interventional

This study is designed to evaluate the efficacy, safety, and pharmacokinetic (PK) profiles of multiple doses of etokimab in adult participants with atopic dermatitis (AD).