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Eczema clinical trials

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NCT ID: NCT05491447 Terminated - Atopic Dermatitis Clinical Trials

A Clinical Trial of BMX-010 in Adult Subjects With Atopic Dermatitis

Start date: January 8, 2023
Phase: Phase 2
Study type: Interventional

Phase 2 clinical trial conducted in 2 parts: Part 1 - Pharmacokinetics and Part 2 - Randomized and Placebo Controlled (subject and clinical assessors will be blinded). Study Product will be applied to AD BID days 1-28. There will be weekly visits from Baseline (day 1) through Day 29. There is a final follow up visit 2 weeks after.

NCT ID: NCT05439941 Terminated - Atopic Dermatitis Clinical Trials

A Long-Term Extension Trial in Participants With Atopic Dermatitis Who Participated in Previous EDP1815 Trials

Start date: June 6, 2022
Phase: Phase 2
Study type: Interventional

This is an Open-Label Extension (OLE) study to evaluate the long-term safety, tolerability, and efficacy of EDP1815 in participants with mild, moderate, and severe atopic dermatitis who have completed the treatment period of a prior clinical study ("parent study") with EDP1815. The current parent study of this protocol is the EDP1815-207 study; A Phase 2, Multicenter, Double-Blind, Placebo-Controlled, Multiple-Cohort Study Investigating the Effect of EDP1815 in Participants for the Treatment of Mild, Moderate and Severe Atopic Dermatitis.

NCT ID: NCT05387707 Terminated - Atopic Dermatitis Clinical Trials

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin as Adjunct Therapy to a Topical Corticosteroid for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis

KIND-1
Start date: August 16, 2022
Phase: Phase 3
Study type: Interventional

This is a two-part, multicenter, randomized, double-blind study to evaluate the efficacy and safety of oral difelikefalin as adjunct therapy to a topical corticosteroid (TCS) for moderate-to-severe pruritus in adult subjects with atopic dermatitis (AD).

NCT ID: NCT05382819 Terminated - Clinical trials for Atopic Dermatitis Eczema

A Safety, Tolerability and Preliminary Efficacy Study of FRTX-02 Capsules in Healthy Subjects and Subjects With Atopic Dermatitis

Start date: May 16, 2022
Phase: Phase 1
Study type: Interventional

FRTX-02 is an orally-available, potent and selective DYRK1A inhibitor.

NCT ID: NCT05253755 Terminated - Atopic Dermatitis Clinical Trials

Study the Safety and Efficacy of DBI-001 Gel Versus Aqueous Gel

Start date: October 6, 2021
Phase: Phase 2
Study type: Interventional

The purpose for this study is to assess the Safety and Efficacy of Daily Application for 4 weeks of DBI-001 Gel Versus Aqueous Gel in Subjects with Atopic Dermatitis

NCT ID: NCT05222516 Terminated - Atopic Dermatitis Clinical Trials

Immunomodulation by OM-85 (Broncho-Vaxom) in Early AD

Start date: December 20, 2021
Phase: Phase 2
Study type: Interventional

Clinical data suggest that treatment with OM-85, by inducing an early contact with bacterial extracts, could modulate the immunity of children with Atopic Dermatitis, and thus play an active role in the treatment of Atopic Dermatitis. The present trial will investigate the influence of administration of OM-85 in the paediatric population younger than 24 months with moderate atopic dermatitis. The efficacy and safety of OM-85 will be evaluated in children aged 3 to 24 months old with moderate Atopic Dermatitis who may benefit from treatment with OM-85. The placebo treatment period will serve as a reference and has been added to establish efficacy and safety.

NCT ID: NCT05200403 Terminated - Atopic Dermatitis Clinical Trials

Improvement In Scratch Behavior And Sleep In Patients With Atopic Dermatitis

PAD
Start date: July 26, 2022
Phase: Phase 4
Study type: Interventional

This single blind study is to primarily evaluate wearable devices and Observer Reported Itch Assessment in children to assess reduction of itch and night-time scratch in response to Crisaborole treatment vs. vehicle treatment (active control comparator without crisaborole) in children with atopic dermatitis (AD). Participants, age 3 months to 11 years with symptomatic mild to moderate AD, along with their primary caregivers will be recruited. The goal of this study is to more fully evaluate the rapid onset of night-time itch and scratch relief, as well as improvements in sleep following treatment with Crisaborole in comparison to vehicle treatment in children with AD. the study will also assess the quality of life (QoL) and sleep within the associated caregivers.

NCT ID: NCT05177328 Terminated - Atopic Dermatitis Clinical Trials

Targeted Investigation of Microbiome Elimination

TIME-1
Start date: July 18, 2022
Phase: Phase 1
Study type: Interventional

The purpose of this study is to examine the pharmacokinetics or survival of new product containing commensal infection fighting bacteria, on the skin of patients with Atopic Dermatitis (AD), after a single application.

NCT ID: NCT04955951 Terminated - Clinical trials for Chronic Atopic Dermatitis

Ultrasonographic Response to Polarized Light Therapy in the Treatment of Atopic Dermatitis

Start date: July 1, 2021
Phase:
Study type: Observational

Non-atopic dermatitis (NAD) or eczema is a common inflammatory condition; potentially debilitating that can compromise quality of life. It is usually seen in childhood, but can onset within or persist into adulthood.

NCT ID: NCT04936113 Terminated - Atopic Dermatitis Clinical Trials

Continued Safety Evaluation of FB-401 in Children, Adolescents and Adults (2 Years and Older) With Mild to Moderate Atopic Dermatitis Previously Enrolled in the FB401-01 Study

Start date: June 2, 2021
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the continued safety and tolerability of FB-401 in subjects 2 years of age or older with mild to moderate atopic dermatitis. FB-401 will be applied topically for up to 48 additional weeks and subjects will be evaluated for safety.