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Eczema clinical trials

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NCT ID: NCT03003793 Completed - Type 2 Diabetes Clinical Trials

Insulin Sensitivity in Patients With Atopic Dermatitis

AD-IF
Start date: November 2015
Phase:
Study type: Observational

The incidence of atopic dermatitis and type 2 diabetes, respectively, has increased over many years. Novel research shows an association between the two conditions. While this relationship at least in theory can be explained by lifestyle factors, there is reason to believe that other pathophysiological mechanisms are involved. Hence, our hypothesis is that patients with atopic dermatitis are insulin resistant due to their chronic inflammatory state. Insulin resistance might play an unknown part in the increased frequency of type 2 diabetes among patients with atopic dermatitis. In the present project, the investigators aim to measure insulin sensitivity by means of the 'golden standard' hyperinsulinaemic euglycaemic clamp in patients suffering from atopic dermatitis compared to a healthy control group (matched case-control study). The project is a close collaboration between The Department of Dermatology and Allergy and Center for Diabetes Research at Gentofte Hospital.

NCT ID: NCT03002571 Completed - Atopic Dermatitis Clinical Trials

Efficacy and Safety of IDP-124 Lotion for the Treatment of Moderate to Severe Atopic Dermatitis in Pediatric and Adult Subjects (301)

Start date: July 24, 2018
Phase: Phase 3
Study type: Interventional

Efficacy and Safety of IDP-124 Lotion for the Treatment of Moderate to Severe Atopic Dermatitis in Pediatric and Adult Subjects

NCT ID: NCT02975206 Completed - Atopic Dermatitis Clinical Trials

Study of the Efficacy, Safety, and Tolerability of Serlopitant for Pruritus (Itch) in Atopic Dermatitis

ATOMIK
Start date: November 2016
Phase: Phase 2
Study type: Interventional

Study of the Efficacy, Safety, and Tolerability of Serlopitant for Pruritus (Itch) in Atopic Dermatitis

NCT ID: NCT02965118 Completed - Atopic Dermatitis Clinical Trials

CAPTAIN-AD: Clinical Study of AmorePacific's TRPV1 Antagonist in Atopic Dermatitis

Start date: November 2016
Phase: Phase 3
Study type: Interventional

This is a phase III study to investigate the safety and efficacy of PAC-14028 cream in Atopic Dermatitis patients.

NCT ID: NCT02950922 Completed - Atopic Dermatitis Clinical Trials

Study of RVT-501 in Adult and Adolescent Subjects With Atopic Dermatitis

Start date: November 2016
Phase: Phase 2
Study type: Interventional

This is a multi-center, randomized, vehicle-controlled, double-blind Phase 2 study in adults and adolescent subjects with mild to moderate atopic dermatitis.

NCT ID: NCT02949960 Completed - Atopic Dermatitis Clinical Trials

DMT210 Topical Gel in the Treatment of Atopic Dermatitis

Start date: October 2016
Phase: Phase 2
Study type: Interventional

The objective of the study is to evaluate the safety and efficacy of DMT210 Gel, 5% compared to vehicle control following 28 days of twice-daily topical application to selected target lesions in male and female patients with mild to moderate atopic dermatitis (AD).

NCT ID: NCT02945683 Completed - Atopic Dermatitis Clinical Trials

Effects of Lactobacillus Reuteri Plus Vitamin D3 in Children With Atopic Dermatitis

Start date: February 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate in a randomized, double-blinded, controlled trial, whether a new food supplement containing Lactobacillus reuteri DSM 17938 and vitamin D3 (Reuterin® D3) may improve the SCORAD in pediatric patients with mild to moderate atopic dermatitis

NCT ID: NCT02945657 Completed - Atopic Dermatitis Clinical Trials

Pharmacokinetics and Safety of MM36 Topical Ointment in Pediatric Subjects With Atopic Dermatitis

Start date: October 2016
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the pharmacokinetic parameters and safety of topical MM36 (OPA-15406) ointment in pediatric subjects with atopic dermatitis under maximal use conditions.

NCT ID: NCT02941432 Completed - Eczema, Dermatitis Clinical Trials

Black Tea Compresses for Facial Eczema and Perioral Dermatitis

Start date: September 1, 2016
Phase: N/A
Study type: Interventional

Facial eczema and perioral dermatitis are clinical entities that develop exclusively in the face and present a special therapeutic challenge. Topical corticosteroids that are commonly applied to treat eczema/dermatitis at other body sites are best avoided in the face, as they may result in rapid atrophy of facial skin and in the long term rather aggravate facial dermatoses. Black tea compresses have been successfully used by German-speaking dermatologists to treat facial eczema/dermatitis for decades. The precise mechanism of action is unknown but is presumably based on astringent properties of tannins in the black tea and on the antiinflammatory action of a wet compress as such. This therapy is cheap, universally available and practically free of side-effects. Despite these perceived advantages the effects and tolerance of black tea compresses have not been formally studied to date. Therefore, the investigators plan to treat 25 patients with facial eczema/perioral dermatitis over a period of 6 days each within the current trial. The disease activity will be assessed before, during and after completion of treatment using several clinical scores. In addition, side-effects, if any, will be documented.

NCT ID: NCT02932891 Completed - Atopic Dermatitis Clinical Trials

An Open Label, Safety Study to Assess the Potential for Adrenal Suppression.

Start date: August 2016
Phase: Phase 2
Study type: Interventional

An Open Label, Safety Study to Assess the Potential for Adrenal Suppression Following Treatment with DSXS in Patients with Atopic Dermatitis