Utility of Lung Clearance Index Score as a Noninvasive Marker of Deployment Lung Disease — LCI  

Dyspnea Clinical Trial

Official title: Utility of Lung Clearance Index Score as a Noninvasive Marker of Deployment Lung Disease

Status Completed

Clinical Trial Summary

The purpose of this study is to learn more about new noninvasive ways of detecting lung disease in US Military personnel and people who worked as contractors during military operations in Iraq and Afghanistan. This study is looking at conducting a type of breathing test called the lung clearance index (LCI) test which is being investigated as a potential noninvasive way to detect the type of lung disease that may be seen in symptomatic deployers retuning from Iraq and Afghanistan.

Clinical Trial Description

The healthy control group will comprise volunteers who are at least 18 years of age, have no history of pre-existing lung disease, and report no respiratory illness in the four weeks preceding enrollment.

The symptomatic deployers who have undergone lung biopsy and meet the case definition for deployment-related lung disease. A case of deployment-related lung disease is defined as the presence of unexplained chest symptoms in a deployer who, on a surgical lung biopsy, is found to have bronchiolitis or granulomatous pneumonitis without other known cause. ;

Related Conditions & MeSH terms

• Bronchiolitis
• Dyspnea
• Lung Diseases
• Pneumonia
• Pneumonitis

• NCT number: NCT03012958
• Study type: Observational
• Source: National Jewish Health
• Status: Completed
• Start date: July 2014
• Completion date: May 2018