Capsaicin for Post-stroke Dysphagia — CADYS  

Dysphagia, Late Effect of Stroke Clinical Trial

Official title: Capsaicin for Post-stroke Dysphagia

Status Recruiting

Clinical Trial Summary

Randomised, double blind, Phase 2 Trial to evaluate the efficacy of oral Capsaicin in patients with post-stroke dysphagia in the (sub-)acute setting.

Clinical Trial Description

After inclusion and the assessment of the swallowing function (PRESS, PAS, FOIS, FEES) patients will be randomised 1:1 to receive 1mcg Capsaicin or Placebo. Oral treatment will be applied 3 times daily either during meals or during regular swallowing tests/trainings accompanied by a Speech Language Pathologist. After re-assessment of the dysphagia after 7 days, patients with persistent dysphagia and applicable for further treatment will be treated for another 23 days with a final clinical swallowing evaluation after a total of 30 days. A Patient Medication Diary will used during the Duration of the Trial to capture compliance. ;

Related Conditions & MeSH terms

• Deglutition Disorders
• Dysphagia, Late Effect of Stroke
• Stroke

• NCT number: NCT04470752
• Study type: Interventional
• Source: Cantonal Hospital of St. Gallen
• Contact: Georg Kägi, Dr.med.
• Phone: +41 71 494 3594
• Email: georg.kaegi@kssg.ch
• Status: Recruiting
• Phase: Phase 2
• Start date: August 24, 2021
• Completion date: December 2024