Clinical Trials Logo

Dyspareunia clinical trials

View clinical trials related to Dyspareunia.

Filter by:
  • Recruiting  
  • Page 1 ·  Next »

NCT ID: NCT06397885 Recruiting - Dyspareunia Clinical Trials

Prospective On Market Patient-reported Outcomes for Milli

POMPOM
Start date: April 30, 2024
Phase:
Study type: Observational

To assess the effectiveness of the Milli device in achieving vaginal intercourse

NCT ID: NCT06059586 Recruiting - Sexual Dysfunction Clinical Trials

Pre-Rehabilitation for Female Patients Undergoing Pelvic Radiotherapy

Start date: January 16, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to examine the feasibility of adding pre-rehabilitation pelvic health physical therapy to standard of care radiation therapy treatment plan for female patients who have been diagnosed with cervical, vaginal, vulvar, uterine, or anal cancer and are a candidate for curative pelvic radiation with external beam. Participants will receive education on using a vaginal dilator for use during treatment and complete questionnaires looking at pain and sexual function.

NCT ID: NCT06000202 Recruiting - Vaginal Atrophy Clinical Trials

Elastographic Improvement of Vaginal Atrophy Treated by Erbium Yag Laser

Start date: August 21, 2023
Phase: N/A
Study type: Interventional

This study is a randomized controlled sham applied study. Its aim is to evaluate the efficacy of Er:YAG laser for the treatment of atrophic vaginitis in postmenopausal women. In this study, demonstration of the efficacy of Er:YAG laser for the treatment of atrophic vaginitis in postmenopausal women is intended with Maturation Index (MI), vaginal pH measurement, Female Sexual Function Index (FSFI), Vaginal Health Index (VaHI), Visual Analogue Scale (VAS) and ultrasonographic elastography

NCT ID: NCT05806203 Recruiting - Female Dyspareunia Clinical Trials

A Study of Participants Ages 21-65 Diagnosed With Dyspareunia and the Effects of Low Intensity Shockwave Treatment

Start date: August 15, 2023
Phase: N/A
Study type: Interventional

Dyspareunia is defined as a complaint of persistent or recurring pain or discomfort associated with attempted or complete vaginal penetration e purpose of this study is to determine the effectiveness of low intensity shockwave treatment for patients with dyspareunia and their ability to tolerate sexual activity, (i.e., penetration of vagina, self or partnered pleasure). Participants will: - Be given a preliminary physical therapy examination and evaluation. - Be asked to attend weekly low intensity shockwave treatment visits. - Be asked to complete 3 Month follow up questionnaires

NCT ID: NCT05586711 Recruiting - Clinical trials for Vulvovaginal Atrophy

Local DHEA and Estradiol on Dyspareunia in Postmenopausal Women

Start date: December 18, 2020
Phase: Phase 4
Study type: Interventional

Vulvovaginal atrophy (VVA) is a condition characterized by vaginal dryness, itching, burning, irritation and dyspareunia. The condition is mainly due to estrogen deficiency and is common during and after menopause. Furthermore, androgens may have an important function in these symptoms. The purpose of the study is to compare vaginal estrogen with vaginal dehydroepiandrosterone (DHEA, an androgen precursor) on dyspareunia (primary outcome), a symptom of VVA in postmenopausal women. Secondary outcomes are total symptom score of VVA (vaginal dryness, irritation/itching, maturation index, pH), clinical signs of VVA, sexual function, urogenital symptoms, vaginal histomorphology, sex hormone levels and short-term safety. The hypothesis of the study is that the treatments will have a similar effect on dyspareunia while DHEA, through local androgenic effects (eg growth of muscle tissue and nerve density in the vaginal wall), may be more effective in treating other related symptoms such as sexual dysfunction. 170 postmenopausal women will be randomly assigned to treatment with either vaginal estrogen (Vagifem) or vaginal DHEA (Intrarosa). The women are examined at the start of the study, after 4 weeks of daily application and after another 8 weeks of treatment with twice a week application of the vaginal treatment. The study is expected to provide increased knowledge about the effect of the treatments of VVA in postmenopausal women as well as whether vaginal DHEA has additional positive effects on sexual function compared to vaginal estrogen.

NCT ID: NCT05540353 Recruiting - Endometriosis Clinical Trials

Transvaginal Low-level Laser Therapy to Improve Pelvic Pain and Sexual Function in Patients With Endometriosis.

Start date: May 2, 2023
Phase: N/A
Study type: Interventional

Dyspareunia is defined as pain with penetrative sexual intercourse. Women with endometriosis have a nine-fold increased risk of dyspareunia, when compared to the general female population. A prospective single-blinded randomized controlled trial will be performed evaluating the change in pelvic pain and sexual satisfaction scores from baseline to 6 weeks after treatment with transvaginal photobiomodulation therapy or sham therapy. Treatment will involve 9 planned treatment sessions over 3-4 weeks. 40 women will be included in the study.

NCT ID: NCT05445115 Recruiting - Dyspareunia Clinical Trials

The Mollie Study, a Study to Evaluate the Safety and Efficacy of the Mollie Medical Device

Start date: September 14, 2021
Phase: N/A
Study type: Interventional

Study to evaluate the use of a medical device in relieving collision dyspareunia

NCT ID: NCT05417334 Recruiting - Dyspareunia Clinical Trials

Effect of Radiofrequency in the Treatment of de Novo Dyspareunia at 4 to 9 Months Postpartum.

Start date: March 18, 2021
Phase: N/A
Study type: Interventional

This study evaluates if the application of resistive capacitive monopolar radiofrequency therapy associated with Thiele massage is effective when treating de novo dyspareunia at 4 to 9 months postpartum.

NCT ID: NCT04885556 Recruiting - Dyspareunia Clinical Trials

Evaluation of a Novel Female Hygiene Device for Postcoital Discomfort

Start date: April 5, 2021
Phase: N/A
Study type: Interventional

Previous research has shown that semen deposition in the vagina after intercourse leads to dripping, discomfort, and vaginal odor. This study is evaluating a hygiene device designed to be inserted into the vagina after intercourse to absorb semen deposited into the vaginal canal to determine if there is a reduction in dripping and odor, and to determine the amount of fluids absorbed.

NCT ID: NCT03782480 Recruiting - Menopause Clinical Trials

Examining Effects of Intrarosa in Women With Genitourinary Syndrome of Menopause/Vulvovaginal Atrophy

Start date: March 2, 2019
Phase: Phase 3
Study type: Interventional

Tissues of the genitals of women are both androgen (testosterone) and estrogen dependent. The clitoris, vestibule, urethra, anterior vaginal wall, peri-urethral tissue, and pelvic floor all depend on androgens for normal function. In addition, the glands, which secrete lubrication during sexual arousal, also require androgens to function. Deficiencies of both estrogens and androgens occur naturally during menopause. Menopause-related deficiencies of these hormones lead to thinning in the tissues of the genital and urinary systems which have been termed Genitourinary Syndrome of Menopause (GSM). Patients with GSM will frequently complain of dryness and/or pain during sexual intercourse. Historically, GSM treatment involved both androgens and estrogens, However, over the past few decades estrogen based therapies have become much more common. More recently, clinical trials have demonstrated that local vaginal dehydroepiandrosterone (Intrarosa®) improves symptoms in menopausal women who have moderate to severe pain with intercourse. Intrarosa® vaginal inserts are a prescription medicine approved by the U.S. Food and Drug Administration (FDA) used in women after menopause to treat moderate to severe pain during sexual intercourse caused by changes in and around the vagina that happen with menopause.