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Dyspareunia clinical trials

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NCT ID: NCT03738605 Recruiting - Breast Cancer Clinical Trials

Vaginal Laser Therapy in Breast Cancer Survivors

Start date: December 1, 2018
Phase: N/A
Study type: Interventional

This study evaluates the efficacy of vaginal CO2 laser therapy in breast cancer survivors with symptoms of Genitourinary Syndrome of Menopause. Half of participants will receive active laser therapy, while the other half placebo therapy.

NCT ID: NCT03714581 Recruiting - Dyspareunia Clinical Trials

Laser Therapy Following Radiotherapy for Gynecological Cancer

Start date: November 15, 2018
Phase: N/A
Study type: Interventional

Women with a history of pelvic radiotherapy due to gynecological cancer, will receive laser therapy for the management of genitourinary syndrome of menopause.

NCT ID: NCT03427255 Recruiting - Dyspareunia Clinical Trials

CBT Group Treatment for Women With Dyspareunia

Start date: September 29, 2017
Phase: N/A
Study type: Interventional

The current study will employ a group CBT treatment program of 10 group sessions and 3 individual couple sessions targeting the thoughts, emotions, behaviors and couple interactions associated with the experience of dyspareunia. Women with superficial dyspareunia and their partners will be randomized to the CBT group program-plus or a waiting list control period at one treatment location in Sweden and two treatment locations in the Netherlands. The waiting-list control period will be comparable to the treatment duration of six months. It is hypothesized that the group program-plus is more effective in improving pain during intercourse in women with superficial dyspareunia compared to women on a waiting-list control period.

NCT ID: NCT03257670 Recruiting - Dyspareunia Clinical Trials

Fractional CO2 Laser Therapy Versus 4% Topical Lidocaine Gel for Dyspareunia in Breast Cancer Survivors

BCLS
Start date: March 20, 2018
Phase: N/A
Study type: Interventional

This trial seeks to determine if therapy with a CO2 laser to the vagina is more effective than lidocaine to the opening of the vagina before intercourse to reduce painful intercourse in women who are breast cancer survivors. This study will also be looking at whether or not the CO2 laser improves pelvic floor function, bowel and bladder function, and sexual function before and after treatment.

NCT ID: NCT03116022 Recruiting - Menopause Clinical Trials

Use of Estriol at Distal Third of Vagina Improving Coital Pain in Post-menopause Women

Start date: June 1, 2017
Phase: Phase 1
Study type: Interventional

Hypoestrogenism leads to vaginal wall changes resulting in diminished vaginal lubrication and, consequently, causing pain during intercourse. Topical estrogen therapy (THT) may control this complaint. However, there are limitations on its use, especially in patients with breast cancer and diagnosed endometrial cancer. This randomized clinical trial aims to assess the impact of local estriol therapy in postmenopausal women complaining of coital pain and to assess serum concentrations of estriol in these women after estriol use. One-hundred-thirty-two women aged between 40 and 65 years will be randomized into three groups: Women using estriol 1 mg / 1g at the proximal third of vagina every other night - estriol proximal group (PEG), women in using estriol 1 mg / 1g at the distal third of the vagina every other night - estriol distal group (DEG), gel group (GG) using water-based during intercourse.

NCT ID: NCT02237131 Recruiting - Pelvic Pain Clinical Trials

Continuous Versus Cyclic Oral Contraceptives for Endometriosis

Start date: April 2014
Phase: Phase 4
Study type: Interventional

To evaluate the efficacy of oral contraceptives in a continuous fashion versus the usual cyclic fashion in the recurrence of endometriosis related symptoms and endometriomas following fertility-sparing surgery.