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Dyslipidemia clinical trials

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NCT ID: NCT02037685 Completed - Dyslipidemia Clinical Trials

Improving Adherence to Statins Among Minority Populations

Start date: June 2010
Phase: N/A
Study type: Interventional

Statins are cholesterol lowering medications that reduce the risk of cardiovascular events. However adherence to these medications has been found to be lower among minorities, a group particularly vulnerable for heart disease. The purpose of this study is to compare the efficacy of a phone based behavioral intervention to mailed educational materials regarding how to control cholesterol and other risk factors. We hypothesized that the behavioral intervention will improve adherence to statins by 15%.

NCT ID: NCT02029625 Completed - Dyslipidemia Clinical Trials

Compare the Pharmacokinetics of NVP-1205 and Coadministration of Rosuvastatin and Ezetimibe

NVP-1205
Start date: February 2014
Phase: Phase 1
Study type: Interventional

The purpose of this study is to compare the pharmacokinetics of NVP-1205 and coadministration of rosuvastatin and ezetimibe.

NCT ID: NCT02028702 Completed - Osteoporosis Clinical Trials

Alternative Treatments for Menopausal Women

Start date: June 2012
Phase: N/A
Study type: Interventional

To investigate the reported health benefits (lipid profile, inflammatory factors, cardiovascular status and bone density) of a novel, phytoestrogen rich, Red Clover treatment on women suffering from both menopause related primary (hot flushes, night sweats, sleep disturbance and weight gain) and secondary (osteoporosis, cardiovascular and changes in lipid metabolism) symptoms.

NCT ID: NCT02013843 Completed - Hypertension Clinical Trials

Treatment of Overweight and Obese Children -Using the "Holbaek-Method" in a Municipality Based Treatment Program.

Start date: March 2013
Phase: N/A
Study type: Interventional

In the present study the effect of a community-based treatment of overweight and obese children is analyzed. The treatment-method is based on the principals and the method used in the Children Obesity Clinic in the Pediatric department i Holbaek. The effect is evaluated by the change in body mass index standard deviation score, change in blood pressure standard deviation score, quality of life and concentration of fasting blood lipids and glucose during one year of treatment.

NCT ID: NCT01990391 Completed - Dyslipidemia Clinical Trials

Brazil Nut Consumption in Microvascular Endothelial Function, Oxidative Stress and Metabolic Abnormalities

Start date: September 2011
Phase: N/A
Study type: Interventional

The purpose this research is to check the effect of Brazil Nuts consumption in oxidative stress, metabolic abnormalities and microvascular endothelial function dyslipidemic and hypertensive patients.

NCT ID: NCT01984073 Completed - Dyslipidemia Clinical Trials

Effects of Niacin On Fatty Acid Trapping

NOFAT
Start date: December 2012
Phase: Phase 1
Study type: Interventional

The purpose of this study is to understand whether a vitamin called NIcotinic ACid vitamIN (NIACIN for short, also known as vitamin B3) helps the body process dietary fat more efficiently. This is important because people with dyslipidemia have a problem with how they process fat, which raise the risk of heart disease.

NCT ID: NCT01970215 Completed - Dyslipidemia Clinical Trials

TA-8995: Its Use in Patients With Mild Dyslipidaemia (TULIP)

TULIP
Start date: August 2013
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to evaluate the efficacy of different doses of TA-8995, a cholesteryl ester transfer protein (CETP) inhibitor, on the elevation of high-density lipoprotein cholesterol (HDL-C) and reduction of low-density lipoprotein cholesterol (LDL-C), alone and in combination with statin therapy. The secondary objectives of this study are to determine the safety and tolerability of TA-8995 in patients with mild dyslipidaemia.

NCT ID: NCT01967355 Completed - Hypertension Clinical Trials

Prolongation of Pregnancy in Preeclampsia by Therapeutic Lipid Apheresis

Start date: April 2013
Phase: N/A
Study type: Interventional

Preeclampsia is a disease which occurs in about 6-8% of all pregnancies and is the main cause of maternal and fetal morbidity and mortality. The cause of preeclampsia is still not clear and the only therapy is preterm caesarean section. In severe preeclampsia an accumulation of triglyceride-rich lipoproteins occurs. Therefore, lipid apheresis is performed as lipid-removing therapy for treatment of preeclampsia in order to prolong pregnancy and provide the fetus more time for maturation. In this individual treatment patients with early preeclampsia (<= 32 weeks of gestation) will be offered a H.E.L.P.-apheresis to postpone caesarean section and therefore prolong pregnancy.

NCT ID: NCT01958775 Completed - Dyslipidemia Clinical Trials

Regulation of Intestinal and Hepatic Lipoprotein Production by Glucagon Like Peptide 2

Start date: March 2012
Phase: Phase 3
Study type: Interventional

1. To assess whether Glucagon like peptide 2 (GLP-2) affects lipoprotein production (study A) 2. To assess whether GLP-2 affects the release of preformed chylomicrons (study B)

NCT ID: NCT01912560 Completed - Clinical trials for Hypercholesterolemia

Pilot Study To Assess CAT-2003 in Patients With Hyperlipidemia

PATHWAYS I
Start date: July 2013
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the safety and efficacy of different doses of CAT-2003 in patients with hyperlipidemia when CAT-2003 is taken for 4 weeks. The study will evaluate effects of CAT-2003 on (1) fasting triglycerides and non-HDL-C in patients with moderate hypertriglyceridemia and (2) fasting LDL-C levels in combination with a statin in patients with hypercholesterolemia who are on a statin.