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Dyskinesias clinical trials

View clinical trials related to Dyskinesias.

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NCT ID: NCT06412653 Not yet recruiting - Epilepsy Clinical Trials

Prospective Pilot Trial to Address Feasibility and Safety of Oral Zinc in GNAO1 Associated Disorders

ZINCGNAO1
Start date: June 2024
Phase: Phase 2
Study type: Interventional

The goal of this clinical trial is to investigate feasibility and safety of an oral therapy with zinc in patients affected by Guanine nucleotide-binding protein G(o) subunit alpha (GNAO1) associated disorders. The main questions it aims to answer are: - Is a daily oral therapy with zinc in GNAO1 associated disorders a safe and feasible therapy? - Are there potential changes in general motor skills, general behaviour and well being, day/night rhythm, level of dyskinesia and dystonia, frequency of seizures, quality of life and changes in the microbiome of the patients. Participants with GNAO1 associated disorders will be given an oral zinc therapy for 6 month and will be assessed in 3 visits and 2 phone calls within this trial.

NCT ID: NCT06298994 Not yet recruiting - Pain Clinical Trials

Determination of Body Awareness and the Functional Movement in Patients With COPD

Start date: March 8, 2024
Phase:
Study type: Observational

The aim of this study is to investigate body awareness and functional movement in patients with Chronic Obstructive Pulmonary Disease (COPD) compared to healthy controls.

NCT ID: NCT06293599 Not yet recruiting - Scapular Dyskinesis Clinical Trials

Effect of Scapular Stabilization Exercises Versus Virtual Reality Exercises in Basketball Players With Scapular Dyskinesia

SD
Start date: March 5, 2024
Phase: N/A
Study type: Interventional

this study will be conducted to compare virtual reality and scapular stabilizing exercise among basketball player with scapular dyskinesia on scapular muscle performance, rounded shoulder, pain intensity , disability and hand grip strength

NCT ID: NCT06218719 Not yet recruiting - Tardive Dyskinesia Clinical Trials

Studying Patterns in Patient Engagement Among Tardive Dyskinesia Patients

Start date: February 2025
Phase:
Study type: Observational

The statistical analysis of the collected data aims to reveal the many factors that influence patient involvement in clinical trials. Findings will be disseminated through conferences and scholarly papers to benefit all parties participating in clinical trials. These findings will help to shape the design of future clinical trials for people with tardive dyskinesia, as well as enhance recruiting techniques and retention rates.

NCT ID: NCT06107829 Not yet recruiting - Clinical trials for Intellectual Disability

Valbenazine Treatment of Tardive Dyskinesia in Adults With Intellectual/Developmental Disabilities

TD-AIDD
Start date: August 2024
Phase: Phase 4
Study type: Interventional

The goal of this open-label clinical trial is to test the safety and efficacy of valbenazine treatment in patients with Intellectual/Developmental Disability (IDD) who have a diagnosis of Tardive dyskinesia (TD). The main questions this study aims to answer are: - Does valbenazine treatment of TD in the previously untreated patient population of adults with IDD produce comparable amelioration of signs of movement disorder as what has historically been reported in adults without IDD? - Is valbenazine treatment of TD in persons with IDD as safe as what has historically been reported in adults without IDD? - Does valbenazine treatment improve Quality of Life (QOL) in persons with IDD and TD treated with valbenazine? - Does valbenazine treatment produce positive change in Activities of Daily Living (ADLs) in persons with IDD and TD? - Does valbenazine treatment of TD in persons with IDD reduce caregiver burden? In this study, 25 participants with IDD and TD will undergo valbenazine treatment for 24 weeks. The participants will be seen for a total of 5 visits: at baseline, and at follow up visits at 3 weeks, 6 weeks, 12 weeks, and 24 weeks. This study does not include a comparison group. Therefore, researchers will compare the response of the study participants to valbenazine treatment with those from a previous reported work that resulted in the FDA approval of this medication.

NCT ID: NCT05858073 Not yet recruiting - Scapular Dyskinesis Clinical Trials

Investigation of Immediate Efficacy of Kinesiology Taping in Individuals With Scapular Dyskinesia

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

Shoulder protraction is the forward tilt of the head with hyperextension of the cervical spine and is associated with lengthening of the sternocleidomastoid and scalene muscles. With the lengthening of the flexor muscles, the weakened and shortened trapezius, levator scapula, and serratus anterior muscles lead to extra flexor torque and sustained contraction.

NCT ID: NCT05637593 Not yet recruiting - Parkinson Disease Clinical Trials

Rhythmic Auditory Stimulation on Upper-limb Movements in PD Patients

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to examine effects of training involving rhythmic auditory stimulation (RAS) on upper-limb movements and functions in patients with Parkinson's disease (PD). Patients will be randomly divided into two groups: the RAS group and the no-RAS group. Patients will receive training with or without the aid of RAS based on their groups. The training task is to use the right hand to take beads from one bowl to another bowl. The box and block test and the Jebsen hand function test will be used before and after training (i.e., pretest and posttest respectively) to assess patients' upper-limb speed and function. Researchers will compare scores of the box and block test and the Jebsen hand function test between the two groups at pretest and posttest to determine effects of RAS.

NCT ID: NCT05516875 Not yet recruiting - Dyskinesias Clinical Trials

Open-Label Extension Study of ASTORIA

Start date: January 31, 2023
Phase: Phase 2
Study type: Interventional

This current open-label extension (OLE) study (JM-010CS-OL) will explore the safety and tolerability of long-term administration of JM-010 of patients who completed 12-week treatment of Phase 2 (JM-010CS03) study.

NCT ID: NCT05424185 Not yet recruiting - Scapular Dyskinesis Clinical Trials

Rate of EMG Rise and Rate of Force Development of Scapular Muscles

Start date: July 1, 2022
Phase:
Study type: Observational

The investigators will clarify rate of electromyography (EMG) rise and rate of force development in overhead athletes on scapular muscles, including upper trapezius, lower trapezius and serratus anterior. The correlation between rate of EMG rise and rate of force development will also be examined.

NCT ID: NCT05053321 Not yet recruiting - Tardive Dyskinesia Clinical Trials

Reduction of Demoralization After Treatment of TD With Valbenazine

Start date: April 2024
Phase: Phase 1
Study type: Interventional

The purpose of this research project is to determine the feasibility of a larger study aimed at demonstrating that treatment of tardive dyskinesia with Valbenazine is associated with reduction of demoralization