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pDIFFIR: Geriatric Periprosthetic DIstal Femur: FIxation Versus Replacement — pDIFFIR  

Distal Femur Fracture Clinical Trial

Official title:
pDIFFIR: Geriatric Periprosthetic DIstal Femur: FIxation Versus Replacement - A Randomized Controlled Trial of Acute Open Reduction Internal Fixation (ORIF) Versus Distal Femur Replacement (DFR)

Clinical Trial Summary

Periprosthetic distal femur fractures are a significant source of morbidity and mortality for elderly patients. One treatment option involved a surgical fixation with plates or nails, screws and cables/wires along the side of your fractured bone. The second method consists in replacing your knee joint with an artificial knee prosthesis (artificial knee joint). The primary objective is to determine if acute distal femur replacement improves knee pain and functional outcomes compared to surgical fixation. Secondary outcomes are mortality, reoperation, complications, post-operative pain and quality of life. A health economic analysis will be conducted to assess the cost-effectiveness of both treatments. A total of 148 patients (74/group) will be enrolled in the study.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05805774
Study type Interventional
Source Unity Health Toronto
Contact Cassandra Tardif-Theriault
Phone 416-864-6060
Email cassandra.tardif-theriault@unityhealth.to
Status Recruiting
Phase N/A
Start date February 1, 2024
Completion date December 10, 2032
View Details
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