Effects of Different Stimuli in Patients With Disorders of Consciousness

Status Completed

Clinical Trial Summary

In recent years, promoting wakening attempts in patients with disorders of consciousness are increasing, but there are a lack of objective indicators to evaluate the efficacy and further researches on the brain mechanism during the wakening processing. So, the study first assessed the cerebral response during emotional acoustic stimuli with quantitative EEG and ERP(Event-related potential), and next, the investigators explored the relationship between brain activation and patients' recovery.

Clinical Trial Description

Auditory stimuli have potential beneficial effects on cognitive functions and consciousness in patients with disorders of consciousness (DOC)，especially the emotional sound; however, precise and accurate quantitative indices to estimate cerebral activation to different auditory stimuli remain scarce. In this study, investigators assessed the response of different brain regions to three acoustic stimuli using quantitative electroencephalography (QEEG) and ERP(Event-related potential),and further investigated the predictive value of QEEG in the prognosis of DOC. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03385291
Study type	Interventional
Source	First Affiliated Hospital of Zhejiang University
Contact
Status	Completed
Phase	N/A
Start date	July 1, 2015
Completion date	July 30, 2017

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