Muscle Analyze In Patient With Disc Herniation

Disk Herniated Lumbar Clinical Trial

Official title:

Comprehensive Analysis Of Muscle Wasting In Disc Herniation

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05245214
• Other study ID #: 06-2021/30
• Status: Completed
• Start date: March 2, 2021
• Est. completion date: January 7, 2022

Study information

• Verified date: February 2022
• Source: Karamanoglu Mehmetbey University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This study which was planned to investigate the factors affecting m. erector spinae (ES), m. multifidus (MF), m. psoas major (PM) and m. quadratus lumborum (QL), which stabilize the lumbar region in the case of disc herniation. In this study, the effects of disc herniation, herniation severity, age, and spinal biomechanics were investigated.

Description:

This study was carried out on 330 individuals with and without lumbar disc herniation. All individuals were divided into 3 groups according to their age. The inclusion criteria: Having only disc degeneration and not having any other neurological or orthopedic disease. Patients who had previous spinal surgery, patients with lumbar scoliosis, spondylolisthesis or structural defect in the sacrum were excluded from the study.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 330
• Est. completion date: January 7, 2022
• Est. primary completion date: January 1, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years to 70 Years

Eligibility

Inclusion Criteria:

• Having only disc degeneration and not having any other neurological or orthopedic disease. Patients who had previous spinal surgery, patients with lumbar scoliosis, spondylolisthesis or structural defect in the sacrum were excluded from the study.

Exclusion Criteria:

• Patients who had previous spinal surgery, patients with lumbar scoliosis, spondylolisthesis or structural defect in the sacrum were excluded from the study.

Related Conditions & MeSH terms

• Disk Herniated Lumbar
• Hernia

Intervention

Diagnostic Test:
• Magnetic Resonance Imaging
Muscle analysis by Magnetic Resonance Imaging

Locations

Country	Name	City	State
Turkey	Karamanoglu Mehmetbey University	Karaman

Sponsors (1)

Lead Sponsor	Collaborator
Karamanoglu Mehmetbey University

Country where clinical trial is conducted

Turkey, 

References & Publications (1)

Sun D, Liu P, Cheng J, Ma Z, Liu J, Qin T. Correlation between intervertebral disc degeneration, paraspinal muscle atrophy, and lumbar facet joints degeneration in patients with lumbar disc herniation. BMC Musculoskelet Disord. 2017 Apr 20;18(1):167. doi: 10.1186/s12891-017-1522-4. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Muscle cross-area	The cross-sectional area of the Multifidus, Erector Spina, Quadratus Lumborum, and Psoas Major muscles on both sides were measured using the T2-weighted axial Magnetig Resonance Imaging.	1 Month
Secondary	Lumbar Biomechanic	Biomechanic analysis was performed by measuring the sagittal curve using T2-weighted sagittal images.	1 Month