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Clinical Trial Summary

Subclinical diastolic dysfunction represents the early phase of diabetic cardiomyopathy and is a common complication among type 2 diabetic patients that increases mortality rate among those patients and can progress to heart failure with preserved ejection fraction. Trimetazidine is an anti-ischemic agent widely used in the treatment of coronary artery disease and it has positive effects on energy metabolism in heart failure. Therefore, we hypothesized that trimetazidine may have potential benefit on the amelioration of the inflammatory insult and improving the clinical outcomes in patients with diabetic cardiomyopathy especially if applied in the early stages.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05556005
Study type Interventional
Source Ain Shams University
Contact heba I serag, Master
Phone 01008344689
Email hebaibrahim92@pharm.asu.edu.eg
Status Recruiting
Phase Phase 2
Start date September 18, 2022
Completion date September 2023

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