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Study to Evaluate MET409 Alone or in Combination With Empagliflozin in Patients With Type 2 Diabetes and NASH

Diabetes Clinical Trial

Official title:
A Phase 2A Study to Evaluate MET409 Alone or in Combination With Empagliflozin in Patients With Type 2 Diabetes Mellitus (T2DM) and Nonalcoholic Steatohepatitis (NASH)

Clinical Trial Summary

A randomized, multi-center study evaluating MET409 (50 mg) alone or in combination with empagliflozin (10 mg) for 12 weeks. Assignment to MET409 will be double-blind and placebo-controlled. Empagliflozin will be incorporated into two of the treatment arms in an open-label manner.

Clinical Trial Description

Subjects assigned to receive empagliflozin will be dosed at 10 mg per day for the duration of the study. Approximately 30 subjects will be enrolled per treatment arm. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04702490
Study type Interventional
Source Metacrine, Inc.
Contact
Status Active, not recruiting
Phase Phase 2
Start date December 15, 2020
Completion date June 2022
View Details
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