Diabetes Mellitus Clinical Trial
Official title:
Evaluation of Microvascular Changes in the Perifoveal Vascular Network Using Optical Coherence Tomography Angiography (OCT-A) in Type I Diabetes Mellitus
Verified date | July 2020 |
Source | Hospital Clinic of Barcelona |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This study is directed to evaluate the role of Optical Coherence Tomography Angiography (OCT-A) in the evaluation of the perifoveal vascular network in type 1 diabetic patients, and to investigate the relationship between OCT-A-derived parameters and demographic and clinical factors, as metabolic control and duration of the disease.
Status | Active, not recruiting |
Enrollment | 600 |
Est. completion date | May 31, 2021 |
Est. primary completion date | March 8, 2021 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 100 Years |
Eligibility |
Inclusion Criteria: - Type 1 Diabetes Mellitus - Healthy controls Exclusion Criteria: - Ocular pathologies other than diabetic retinopathy (i.e. age-related macular degeneration, retinal vein occlusions, uveitis, glaucoma, etc.) - Axial length: <-6.00 to >+3.00 diopters - Media Opacities - Unability to capture OCT images |
Country | Name | City | State |
---|---|---|---|
Spain | Diabetes Unit, Institut Clinic de Malalties Digestives i Métaboliques (ICMDM), Hospital Clínic de Barcelona | Barcelona | |
Spain | Institut Clinic de Oftalmologia (ICOF), Hospital Clínic de Barcelona | Barcelona |
Lead Sponsor | Collaborator |
---|---|
Hospital Clinic of Barcelona | Fundació La Marató de TV3 |
Spain,
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* Note: There are 16 references in all — Click here to view all references
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Perifoveal vessel density | OCTA images will be processed to obtain vascular density measurements in this area (mm-1) | 24 months | |
Secondary | Parafoveal vessel density | OCTA images will be processed to obtain vascular density measurements in this area (mm-1) | 24 months | |
Secondary | Total Avascular Area | OCTA images will be processed to obtain total avascular area measurements (mm2) | 24 months | |
Secondary | Foveal Avascular Zone | OCTA images will be processed to obtain foveal avascular zone area measurements (mm2) | 24 months |
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