Diabetes Mellitus, Type 2 Clinical Trial
Official title:
Treating Periodontal Infection: Effects on Glycemic Control in People With Type 2 Diabetes
Verified date | July 2017 |
Source | University of Michigan |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The purpose of this project is to obtain important preliminary data necessary to support design of a full scale, multicenter randomized clinical trial (RCT) to evaluate the effect of treating periodontal infection on glycemic control in type 2 diabetes mellitus.
Status | Completed |
Enrollment | 46 |
Est. completion date | September 3, 2004 |
Est. primary completion date | September 3, 2004 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria - Subjects must be 18 years of age or older, - have at least six natural teeth, - have established periodontal disease (established at the screening examination), - have a history of type 2 diabetes of at least six months with HbAlc > 7.1%. Exclusion Criteria - Subjects will be excluded from the study if they are presently under the care of a periodontist; - have had antibiotic treatment within the previous three months; - have conditions that require antibiotic prophylaxis for dental treatment; - have allergies to iodine, doxycycline, metronidazole, or chlorhexidine; - have blood dyscrasias; - are pregnant or breast feeding; - have severe cognitive or communication impairment; - have a cardiac pacemaker; - are under cancer chemotherapy; - are medically unstable or have a life expectancy of less than two years; - are currently taking disulfiram, phenobarbital, lithium, terfenadine, astemizole, or warfarin; - or are out of town or otherwise unavailable for more than three consecutive months of the year. |
Country | Name | City | State |
---|---|---|---|
United States | Department of Cariology, Restorative Sciences and Endodontics | Ann Arbor | Michigan |
Lead Sponsor | Collaborator |
---|---|
University of Michigan | National Institute of Dental and Craniofacial Research (NIDCR) |
United States,
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