Diabetes Mellitus Clinical Trial
Official title:
Identification of Biomarkers Derived From Adipose Tissue With Potential Utility in the Diagnosis and Prognosis of Cardiovascular Risk of the Obese Patient.
This study evaluates the relationship between the adipose tissue, as an active component, which can define metabolic phenotypes linked to cardiovascular risk modification post bariatric surgery.
Bariatric surgery induces a significant reduction in co-morbidities associated with obesity,
such as Diabetes mellitus, dyslipidemia, liver disease, arterial hypertension, obstructive
apnea and cardiovascular risk. However this does not happen in all obese patients, even when
there is a weight reduction.
It is known that the adipose tissue is actively involved in synthesis of cytokines and its
role in metabolic phenotypes has been suggested. It is possible that the intrinsic mechanisms
of adipose tissue participate in several benefits observed in morbidly obese patients who
undergo to an anti-obesity surgery.
So this study explores the involvement of adipose tissue as an active component, which can
define metabolic phenotypes linked to cardiovascular risk modification post bariatric
surgery.
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